@article {1602, title = {Antibacterial Effectiveness of Morinda Citrifolia L. Extract on Salmonella Typhi Bacteria Using Serial Dilution Method with 15 - 60 Minutes Contact Time}, journal = {Pharmacognosy Journal}, volume = {13}, year = {2021}, month = {July 2021}, pages = {839-843}, type = {Original Article}, chapter = {839}, abstract = {

Noni fruit (Morinda citrifolia L.) contains phenol and flavonoid compounds which can function as natural antibacterials with the highest phenol content obtained from ripe Morinda citrifolia L. fruit. Phenolic compounds have been widely studied as disinfectants against broadspectrum antibacterials, namely Gram-positive and Gram-negative bacteria. This study aims to determine the effectiveness of the inhibitory power of ripe Morinda citrifolia L. extract against the growth of gastroenteritis-causing bacteria with the serial dilution method at concentrations of 40\%, 60\%, 80\%, and 100\% with variations in a contact time of 15 {\textquoteright}, 30{\textquoteright}, 45 {\textquoteright}and 60{\textquoteright}. Then proceed with a concentration of 10\%, 20\%, 30\%, and 40\% with the same variation in contact time. The results showed that all concentrations of ripe Morinda citrifolia L. extract and the variation in contact time could inhibit the growth of S.Typhi bacteria with a minimum inhibitory concentration at a concentration of 10\% with a contact time of 15 minutes. It needs to be continued with a toxicity test before it is used in the community.

}, keywords = {Morinda citrifolia L., S. Typhi, Serial dilution}, doi = {10.5530/pj.2021.13.107}, author = {Wawan Sofwan Zaini} } @article {905, title = {The Effect of Noni Fruit Extract (Morinda citrifolia L.) in Gingivitis Patient}, journal = {Pharmacognosy Journal}, volume = {11}, year = {2019}, month = {July 2019}, pages = {678-682}, type = {Original Article}, chapter = {678}, abstract = {

Introduction: Antiseptic mouthwash (chlorhexidine and povidone iodine) is usually used to decrease the number of colonies of pathogenic bacteria. But, somehow it gives side effect if it used for a long time. So, it should take another alternative as a raw material to make a mouthwash with minimal side effects, economical and efficacious. Aim: The aim of this research was to examine the effect of noni fruit extract (Morinda citrifolia L.) that given as mouthwash on 15 gingivitis patients. Materials and Methods: The research was conducted for 7 days in a row and gingival index of each patient was measured before and after the treatment. The patients were divided into 3 group and given 3 different treatments. Group I used mouthwash noni fruit extract 5\%; Group II used chlorhexidine 0.1\%; and Group III used a mixture of extracts of noni: chlorhexidine (2.5\% : 0.05\%). The mouthwash was used in the morning and at the night before going to sleep as much as 15 ml and gargling it for 30 sec. Results: The results showed the gingival index was declined in every group treatment (mouthwash noni fruit extract 5\%, chlorhexidine 0.1\% and a mixture of extracts of noni: chlorhexidine (2.5\% : 0.05\%). The differences between each group were not significant (p \> 0.05). Conclusion: Despite it give the same effect, the extract of noni fruit should be used as an alternative to mouthwash because it gives the same effect as much as chlorhexidine and it also economical, efficacious and minimal side effects.

}, keywords = {Chlorhexidine, Gingival index, Morinda citrifolia L., Mouthwash, Noni fruit extract}, doi = {10.5530/pj.2019.11.107}, author = {Yufri Aldi and Hasanatul Khairiyah and Nila Kasuma and Afriwardi and Agus Sri Banowo} }