01810nas a2200265 4500008004100000245011700041210006900158260001800227300001100245490000600256520102600262653000801288653000901296653003001305653002601335653000901361653000901370653003101379653000801410100001601418700002301434700002801457700002501485856003401510 2017 eng d00aIn-vivo Hepatoprotective Activity of Methanolic Extracts of Sphaeranthus amaranthoides and Oldenlandia umbellate0 aInvivo Hepatoprotective Activity of Methanolic Extracts of Sphae cNovember 2016 a98-1010 v93 a
Objective: The present study was carried out to evaluate the in vitro hepatoprotective activity of unexploited plants, Sphaeranthus amaranthoides and Oldenlandia umbellate on CCl4 induced liver injury, which are indigenous to South India. Methods: in the present study the methanolic extracts from Sphaeranthus amaranthoides and Oldenlandia umbellata were studied against the carbon tetrachloride hepatotoxicity. Results: significant hepatoprotective effect was obtained against carbon tetrachloride induced liver damage as judged from serum marker enzyme activities (SGOT, SGPT, ALT, and TB) and a normal architecture of liver compare to toxic control. Conclusion: the result revealed that methanolic extracts of Sphaeranthus amaranthoides and Oldenlandia umbellata could be useful in preventing CCl4 induced liver injury.
10aALP10aCCl410aHepatoprotective activity10aOldenlandia umbellata10aSGOT10aSGPT10aSphaeranthus amaranthoides10aTB.1 aDe, Somnath1 aSuresh, Ramalingam1 aBabu, Akula, Murali Sri1 aAneela, Siddabathuni uhttp://phcogj.com/article/233