01573nas a2200217 4500008004100000245012500041210006900166260001300235300001200248490000600260520088100266653002401147653002001171653002101191653002401212653001901236100002401255700001801279700002001297856003801317 2017 eng d00aApoptosis Induction of Cervical Carcinoma HeLa Cells Line by Dichloromethane Fraction of the Rinds of Garcinia cowa Roxb0 aApoptosis Induction of Cervical Carcinoma HeLa Cells Line by Dic cMay 2017 a475-4780 v93 a
Objective: This study aims to determine the apoptosis induction of HeLa cervical carcinoma cells death by dichloromethane fraction of the rinds of Garcinia cowa Roxb. Methods: Apoptosis induction of HeLa cell line was observed using a double staining method. Results: The result of double staining observation showed that an apoptosis occurs which marked with yellowish green fluorescence and cell fragmentation. The average percentage of apoptotic cells was higher in the treated variables (70.38%) compared to the control variables (12.26% ). Statistical analysis by Independent Sample T-Test showed apoptosis Sig. (2-tailed) = 0.000 (<0.025). Conclusion: The dichloromethane fraction of G. cowa rind induces apoptosis in HeLa cervical cancer cells.
10aApoptosis induction10aCarcinoma cells10aDouble stanining10aGarcinia cowa Roxb.10aHeLa cell line1 aWahyuni, Fatma, Sri1 aFebria, Siska1 aArisanty, Dessy u/files/PJ-9-4/10.5530pj.2017.4.76