TY - JOUR T1 - Preliminary Phytochemical analysis and In vitro Antioxidant, FTIR Spectroscopy, Anti-diabetic activity of Acacia catechu ethanolic seed extract JF - Pharmacognosy Journal Y1 - 2015 A1 - Thangavelu Lakshmi A1 - Rajendran Ramasamy A1 - Rathinam Thirumalaikumaran KW - Acacia catechu seed KW - Alpha glucosidase KW - Alpha-amylase KW - Antidiabetic KW - Antioxidant KW - FTIR Spectroscopy KW - Phytochemical AB -

Objective: To evaluate the preliminary phytochemical analysis and in vitro antioxidant activity, anti-diabetic effect of ethanolic seed extract of Acacia catechu against the alpha amylase and alpha glucosidase digestive enzymes in the pancreas and small intestine. Methods: Preliminary phytochemical analysis was done by adopting the method of Evans. Antioxidant assay is performed by DPPH, ABTS and FRAP assay, Anti diabetic activity was determined by modified method of miller, the extract at different concentrations was tested for mammalian alpha amylase and alpha glucosidase enzyme inhibitory assay under the controlled experimental conditions and subjected to determination of absorbance. Results: The present study reveals the presence of few secondary metabolites and the extract exhibits potent Antioxidant activity and a concentration dependent inhibition of Alpha amylase and Alpha glucosidase. Conclusion: From the present study it can be concluded that ethanolic seed extract of Acacia catechu possessed marked in vitro antioxidant and anti-diabetic effect. The effect was plausibly due to the presence of phenolic contents of Acacia catechu

VL - 7 IS - 6 ER -