@article {1035, title = {Chemical Constituents and Antifungal Activity of Leaf Essential Oil from Oreopanax ecuadorensis Seem. (Pumamaki), Endemic Plant of Ecuador}, journal = {Pharmacognosy Journal}, volume = {11}, year = {2019}, month = {November 2019}, pages = {1544-1548}, type = {Research Article}, chapter = {1544}, abstract = {

Background: Oreopanax ecuadorensis Seem. is a plant from Ecuador, that is found in the Andean region of the country. The plant is commonly used in protective rituals, and as an antiflu, analgesic and disinfectant medicine. Aim: The research aims to extract and analyze the chemical composition and evaluation of its antifungal potential of the essential oil extracted from its leaves. Methods: steam distillation was used for the extraction of essential oil, the evaluation of its components was performed by GC/MS, and the antifungal evaluation by the disc diffusion method. Results: The essential oil was obtained with a yield of 0.05\%. 33 compounds were detected of which 30 were identified, corresponding to 99.28\%; the most abundant molecules were: thujene \<α-\> (36.63\%), followed by bicyclogermacrene with (8.76\%), pinene \<β-\> with (8.32\%) and limonene with 5.15\%. Three of the four strains evaluated were affected by the oil at concentrations of 1.25\%, inhibiting its growth. The strains were: Trichophyton mentagrophytes, Trichophyton rubrum and Microsporum canis. Conclusion: The essential oil shows good antifungal activity, which could be less than 1.25\%. In this way, this medicinal plant is valued by verifying ancestral knowledge in the use of medicinal plants by the Andean people of Ecuador.

}, keywords = {Antifungal activity, GC/MS, Oreopanax ecuadorensis, Puma Maki}, doi = {10.5530/pj.2019.11.236}, author = {Paco Noriega and Bryan Vergara and Carlos Carillo and Tatiana Mosquera} }