@article {1254,
	title = {Anti-inflammatory and Cytotoxic Effect of Arrow Root Mediated Selenium Nanoparticles},
	journal = {Pharmacognosy Journal},
	volume = {12},
	year = {2020},
	month = {September 2020},
	pages = {1363-1367},
	type = {Research Article},
	chapter = {1363},
	abstract = {<p class="rtejustify">Nanoparticles serve to reduce toxicity, enhance bioactivity and improve targeting. Selenium nanoparticles (SeNPs) are explored because of it{\textquoteright}s unique characteristics and various known therapeutic benefits such as antioxidants activities and reducing risk of cancer. In this study, arrow root which is a starch obtained from tapioca or cassava is mediated with SeNPs and studied for it{\textquoteright}s anti-inflammatory and cytotoxic effect. The plant extract of arrow root was prepared and mixed with the sodium selenite solution. The solution is kept in a magnetic stirrer while being observed for any colour change. The synthesis of nanoparticles is observed using UV-vis spectrophotometry. Then the anti-inflammatory activity is observed using albumin denaturation assay and cytotoxic analysis conducted on brine shrimp nauplii. The results showed that there was a lower toxicity rate of SeNPs and significant anti-inflammatory activity which concludes that these nanoparticles can be used in various drug designing aspects in future.</p>
},
	keywords = {Anti-inflammatory, Brine shrimp, Green synthesis, Selenium nanoparticles},
	doi = {10.5530/pj.2020.12.188},
	author = {Twinkle Francis and S Rajeshkumar and Anita Roy and T Lakshmi}
}
