@article {2057, title = {Effects of Melissa officinalis essential oil on state and trait anxiety}, journal = {Pharmacognosy Journal}, volume = {15}, year = {2023}, month = {June 2023}, pages = {454-460}, type = {Research Article}, chapter = {454}, abstract = {

Introduction: Essential oils are complex substances used extensively in aromatherapy and phytotherapy, some of them as anxiety and stress-relieving agents. In order to evaluate the effects of Melissa officinalis essential oil on state and trait anxiety, this study was conducted. Methods: The essential oil was extracted by steam distillation and the chemical composition was investigated by Gas chromatographymass spectrometry (GC{\textendash}MS). In addition, a Quasi experimental study with measures at pretest-posttest was conducted, where 58 participants were divided into two groups, a waiting-list (WL) control group, and an experimental group (EG)treated with aromatherapy based on Melissa officinalis essential oil. The anxiety index was evaluated by State-Trait Anxiety Inventory (STAI). Measures were taken at two times: pretest and posttest. Results: The chemical analysis showed that β-cubebene (26.3\%), β-caryophyllene (25.4\%) and geranial (12.5\%) were de main components. Both state and trait anxiety levels decreased in the experimental group during the posttest phase; however, only state anxiety demonstrated statistically significant differences (p\<0.05). A moderate size effect was found for state anxiety (d = 0.799; g= 0.797) with 1-β=0.803; but none for trait anxiety. Conclusion: Melissa officinalis essential oil was moderately effective on state anxiety but has no effect on trait anxiety.

}, keywords = {Essential oil, Melissa officinalis., State anxiety, Trait anxiety}, doi = {10.5530/pj.2023.15.101}, author = {Paul Alan Arkin Alvarado-Garc{\'\i}a and Maril{\'u} Roxana Soto-V{\'a}squez and Francisco Mercedes Infantes Gomez and Natalia Mavila Guzm{\'a}n Rodr{\'\i}guez and Yolanda Elizabeth Rodr{\'\i}guez de Guzm{\'a}n and Demetrio Rafael Jara-Aguilar and Roger Antonio Rengifo-Penadillos and Jos{\'e} Gilberto Gavidia-Valencia and Iris Melina Alfaro-Beltr{\'a}n} }