@article {2320,
	title = {Expression of Matrix Metalloproteinase-9, Transforming Growth Factor Beta and Fibroblast in The Simblefaron Due to Alkali Burn: Literature Review},
	journal = {Pharmacognosy Journal},
	volume = {16},
	year = {2024},
	month = {June 2024},
	pages = {687-690},
	type = {687-690},
	chapter = {687},
	abstract = {<p class="rtejustify">Simblefaron is one of the most challenging complications in the late stages of an alkali burn. Symblepharon characteristically resembles connective tissue or bands that protrude from the eyelid{\textquoteright}s interior surface (palpebral conjunctiva) to the surface of the eyeball (bulbar conjunctiva). This literature review was conducted to see the molecular mechanism of symblepharon formation. Matrix metalloproteinase (MMP- 9), transforming growth factor (TGF-β), and Fibroblast played a significant part in the healing of conjunctival wounds. MMP-9, TGF-β, and fibroblast overexpressed are suspected to cause excessive inflammation and fibrosis, which results in symblepharon. By knowing this, it is hoped that it can become a basis for developing appropriate management for the occurrence of simblepharon.</p>
},
	keywords = {Alkali, Burn, Conjunctiva, Symblepharon},
	doi = {10.5530/pj.2024.16.115},
	author = {Dian Mayangsari and Lukisiari Agustini and Susy Fatmariyanti and Ridholia and Pudji Lestari}
}
