@article {771, title = {Total Phenolic Content and Tyrosinase Inhibitory Potential of Extracts from Cajanus cajan (L.) Millsp.}, journal = {Pharmacognosy Journal}, volume = {10}, year = {2018}, month = {November 2018}, pages = {s109-s112}, type = {Original Article}, chapter = {s109}, abstract = {

Background: Cajanus cajan (L.) Millsp. (Fabaceae) is a legume plant which used for human food and animal feed. Objective: The present study was aimed to investigate total phenolic content and tyrosinase inhibitory potential of the root, stem and seed parts of C. cajan. Method: Crude extracts were prepared by reflux extraction using methanol, dichloromethane and water as solvents. Total phenolic contents of the obtained extracts were analyzed by Folin- Ciocalteu colorimetric method and the inhibitory effect on tyrosinase activity was determined spectrophotometrically. Results: The results revealed that dichloromethane seed extract had more total phenolic content than those of methanol and water seed extracts, respectively. Dichloromethane seed extract had the highest total phenolic content of 92.00 \± 1.24 mg GAE/ g extracts. However, the highest tyrosinase inhibitory activity was found in the root methanol extract with IC50 of 3.55 \± 0.35 mg/ml. Conclusion: Type of extraction solvent was an important factor on phenolic contents of C. cajan extracts. The extracts of C. cajan inhibit slightly tyrosinase inhibitory.

}, keywords = {Cajanus cajan, Dichloromethane seed extract, Root methanol extract, total phenolic content, Tyrosinase inhibitor}, doi = {10.5530/pj.2018.6s.21}, author = {Prasob-on Rinthong and Suthira Maneechai} } @article {430, title = {Total Phenolic Contents and Free Radical Scavenging Activity of Guaiacum officinale L. Extracts}, journal = {Pharmacognosy Journal}, volume = {9}, year = {2017}, month = {September 2017}, pages = {929-931}, type = {Original Article}, chapter = {929}, abstract = {

Backgound: Guaiacum officinale L. is an alien species to Thailand. It is used as anti-arthritis and anti-rheumatoid agents in Indian folklore medicine. Objective: The present study was aimed to investigate total phenolic contents and free radical scavenging activity of the extracts from Guaiacum officinale L. (Zygophyllaceae). Methods: The plant parts including bark, twig and leaf were extracted using different solvents (ethyl acetate, water and ethanol). Total phenolic contents were determined by Folin-Ciocalteu Colorimetry method while free radical scavenging activity of the extracts was investigated by 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity assay. Results: The results show that the highest total phenolic content is found in the ethyl acetate twig extracts (20.3\±0.0031 \μg GAE/1 \μg extracts). The ethanolic twig extracts had the highest free radical scavenging activity with IC50 of 0.45\±0.0188 mg/ml. Conclusion: The extracts from Guaiacum officinale L. exhibit good anti-oxidant activity and may be suitable for development as drugs and supplementary food.

}, keywords = {Ethanolic twig extracts, Ethyl acetate twig extracts., Free Radical Scavenging Activity, Guaiacum Officinale L, Total Phenolic Contents}, doi = {10.5530/pj.2017.6.145}, url = {http://fulltxt.org/article/198}, author = {Suthira Maneechai and Vachiraporn Pikulthong} }