@article {701, title = {Antiurolithiatic Activity of Daucus carota: An In vitro Study}, journal = {Pharmacognosy Journal}, volume = {10}, year = {2018}, month = {August 2018}, pages = {880-884}, type = {Original Article}, chapter = {880}, abstract = {

Context: Urolithiasis is a polygenic disorder with complex etiology and even complicated treatment outcomes. Daucus carota is a widely cultivated crop with traditional claims for its antiurolithiatic potential. Aim: Present study was an attempt to investigate the antilithic potential of D. carota root extract (DCRE) against calcium oxalate (CaOx) urolithiasis by employing in vitro methods. Methods: Nucleation, growth and aggregation assay of CaOx crystallization were used. FT-IR analysis was used for characterizing CaOx crystals. Results: DCRE exhibited significant inhibition of nucleation, growth and aggregation of CaOx crystals. It produced a favorable morphological transformation of CaOx crystals from calcium oxalate monohydrate to calcium oxalate dihydrate. FT-IR analysis confirmed formation of calcium oxalate monohydrate crystals to be utilized for growth and aggregation assays. Conclusion: DCRE possesses significant antiurolithiatic activity against CaOx urolithiasis in vitro which could be attributed to its saponins, tannins, flavonoids and polyphenolic content.

}, keywords = {Aggregation, Flavonoids, FT-IR, Nucleation, Urolithiasis}, doi = {10.5530/pj.2018.5.148}, author = {Sweta Bawari and Archana Negi Sah and Devesh Tewari} } @article {592, title = {Pharmacognostical Evaluation of Rhododendron arboreum Sm. from Uttarakhand}, journal = {Pharmacognosy Journal}, volume = {10}, year = {2018}, month = {March 2018}, pages = {527-532}, type = {Original Article}, chapter = {527}, abstract = {

Objective: Rhododendron arboreum Sm. commonly known as Burans is an important plant of the Himalayan region. It is the national flower of Nepal and state tree of Uttarakhand. The present study pertains to the pharmacognostical evaluation of R. arboreum from Uttarakhand. Methods: Macroscopy, microscopy by free hand section cutting and with the help of scanning electron microscopy (SEM) were done along with the physicochemical analysis. Preliminary phytochemical studies and fluorescence analysis was also carried out. Results: Results revealed that the leaves contain paracytic or amphiparacytic stomata in cluster form. The epidermal cells were long and spongy. The cells also contain some grooves and papillae throughout the surface. Preliminary phytochemical analysis showed the presence of different secondary metabolites like alkaloids carbohydrates, phenols, proteins, saponins, and tannins. Conclusion: R. arboreum from Uttarakhand region was investigated for its morphological and cytological characteristics with the help of scanning electron microscopy for the first time. The results provide details on the presence of several specific characters which are important for the identification of the genuine crude drug.

}, keywords = {Burans, Himalaya, microscopy, Phytochemical, SEM}, doi = {10.5530/pj.2018.3.86}, url = {http://fulltxt.org/article/519}, author = {Devesh Tewari and Archana Negi Sah and Sweta Bawari} }