@article {1624, title = {Isolation and Structural Characterization of Compounds from Blumea lacera}, journal = {Pharmacognosy Journal}, volume = {13}, year = {2021}, month = {July 2021}, pages = {999-1004}, type = {Research Article}, chapter = {999}, abstract = {

Background: The medicinal plants consider as a rich resource of ingredients which can be used in drug development and synthesis. Blumea lacera (Burm. f.) DC. is generally used in traditional medicine for the treatment of cough, bronchitis, dysentery, wound healing. The aim of this study is to isolate and identify the compounds from the aerial parts of Blumea lacera. Methods: The aerial parts of B. lacera were dried, powdered and extracted using EtOH, and the concentrated extract was partitioned in succession with n-hexane, CH2Cl2, and EtOAc. From the EtOAc fraction, the compounds were isolated through column chromatography and their chemical structures were elucidated by NMR spectroscopy and confirmed by comparison of their NMR data with literature data. Results: Repeated column chromatography of the EtOAc-soluble fraction from the aerial parts of B. lacera resulted in the isolation of β-sitosterol (1), campesterol (2), artemetin (3) and acid paracatechuic (4).

}, keywords = {Asteraceae, Blumea lacera, Column chromatography, Flavonoid}, doi = {10.5530/pj.2021.13.129}, author = {Xuan Phong Pham and Tran Thi Tuyet Nhung and Hoai Nam Trinh and Do Minh Trung and Dang Truong Giang and Binh Duong Vu and Nguyen Trọng Diep and Nguyen Van Long and Van Thu Nguyen and Chu Van Men} } @article {1323, title = {A New Ursane-Type Triterpene from the Fermented Shallot Allium Ascalonicum}, journal = {Pharmacognosy Journal}, volume = {13}, year = {2021}, month = {January 2021}, pages = {01-07}, type = {Original Article}, chapter = {01}, abstract = {

3,24-acetonideclethric acid (1), a new ursane-type triterpene, and four known compounds including ursolic acid (2), randiasaponin IV (3), ilekudinoside W (4) and (25S)-1β,3β,24β- trihydroxyspirost-5-en 1-O-α-L-rhamnopyranosyl-(1{\textrightarrow}2)- α-L-arabinopyranoside (5), and were isolated from the fermented shallot Allium ascalonicum. Their structures were determined by analysis of HR-ESI-MS, NMR spectral data, as well as comparison with those reported in the literature. All of the saponins (3-5) exhibited antimicrobial activity against three strains Staphylococcus aureus, Escherichia coli, and Candida albicans with IC50 values in the range from 89.49 {\textpm} 2.24 to 95.71 {\textpm} 3.86 μM.

}, keywords = {24-Acetonideclethric acid, 3, Allium ascalonicum, Antimicrobial activity, Saponin}, doi = {10.5530/pj.2021.13.1}, author = {Nguyen Van Chuyen and Nguyen Hong Son and Pham Van Hien and Dang Truong Giang and Ho Ba Ngoc Minh and Ngo Thi Tuyet Mai and Chu Van Men and Ho Anh Son and Vu Binh Duong} }