@article {2602, title = {Integrating Ancient Therapeutics into Nutraceutical Oral Films for Alzheimer{\textquoteright}s Neuroprotection}, journal = {Pharmacognosy Journal}, volume = {18}, year = {2026}, month = {June 2026}, pages = {120-128}, type = {Original Article}, chapter = {120}, abstract = {

Background: There are many popular neuroprotective medicinal plants mentioned in Indian traditional medicine systems which need to made available to Alzheimer{\textquoteright}s patients in suitable dosage form. Objectives: Herbal nutraceutical in the form of oral fast dissolving film (OFDF) containing bioactive enriched fractions of traditionally well-known Indian nootropic plants will enhance neuroprotective efficacy and quality of life of Alzheimer{\textquoteright}s patients. Materials and Methods: The standardized extracts of Centella and Bacopa are prepared and formulated into oral films which further evaluated for pharmaceutical parameters, stability, safety and behavioural animal studies. Results and Conclusion: The modernised dosage form of traditional medicines in the form of oral films found to reduce dosage frequency due to enhanced bioavailability of bioactive enriched herbal extracts and is easy for administration to Alzheimer{\textquoteright}s patients. Behavioural animal studies exhibited promising multitargeted neurocognitive efficacy of developed oral films.

}, keywords = {Alzheimer{\textquoteright}s disease, Bacopa monnieri, Convolvulus pluricaulis, Dementia, neurocognitive efficacy, Withania somnifera}, doi = {10.5530/pj.2026.18.125}, author = {Sharada L. Deore and Anjali A kide and Bhushan A. Baviskar and Bhavana A. Shende} } @article {2043, title = {Evaluation of Neuroprotective Efficacy of Indian Shankhpushpi Varieties in Alzheimer{\textquoteright}s disease {\textendash} North Vs South}, journal = {Pharmacognosy Journal}, volume = {15}, year = {2023}, month = {June 2023}, pages = {372-377}, type = {Research Article}, chapter = {372}, abstract = {

Background: Shankhpushpi is a well-known Ayurvedic memory enhancing medicine associated with controversy. Among the various varieties, Convolvulus pleuricaulis and Clitorea ternatia are widely used in commercial memory enhancing formulations under the name of Shankhpushpi. Convolvulus pleuricaulis is recognized as true shankhpushpi in North side of India, however in southern part of India, Clitorea ternatia is accepted as Shankhpushpi. Objectives: The present study aims to compare neuroprotective efficacy of C. pleuricaulis and C. ternatea by in vitro, in vivo methods and establish scientifically validated data to choose appropriate shankhpushpi variety for commercial use. Materials and Methods: Both herbs were extracted in the Soxhlet apparatus with 70\% ethanol for 5 - 6 hours at 60 - 65ĚŠ C. The presence of neuroprotective principles - taraxerol and scopoletin in extracts was confirmed by the Thin Layer Chromatography. The preliminary screening for neuroprotective efficacy of extracts was done by in vitro free radical scavenging, Acetyl cholinesterase enzyme inhibition and LOX enzyme level estimation. Invivo study of extracts included behavioral assessment of adult rats by Y maze, Morris water maze using scopolamine induced Alzheimer{\textquoteright}s disease like model. Result: Extracts of both C. pleuricaulis and C. ternatea significantly scavenged free radicals, inhibited acetyl cholinesterase and LOX enzyme in vitro. But in in-vivo study, significant retention of spatial and working memory was observed in rats administered with C. pleuricaulis as compared to C. ternatea. Conclusion: C. pleuricaulis more significantly shields against memory loss and dementia by reducing oxidative stress, inflammation, and memory impairment. Hence should be used in commericial neuroprotective formulation as chief source of Shankhpushpi instead of C. ternatea.

}, keywords = {Alzheimer{\textquoteright}s disease, Dementia, Scopolamine, Scopoletin., taraxerol}, doi = {10.5530/pj.2023.15.87}, author = {Sharada L. Deore and Anjali A. Kide and Bhushan A. Baviskar and Somshekhar S. Khadabadi and Bhavana A Shende} } @article {1509, title = {Development and Antifungal Evaluation of Cinnamaldehyde Containing Silver Nanoparticles against Candida albicans}, journal = {Pharmacognosy Journal}, volume = {6}, year = {2014}, month = {2nd July 2014}, pages = {63-65}, type = {Letter To The Editor}, abstract = {

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}, keywords = {Letter to the Editor}, author = {Sharada L. Deore and Sharad Chaudhari and Bhushan A. Baviskar and Somshekhar S. Khadabadi} }