@article {2612, title = {Effectiveness of Family Empowerment Based on Arui Sai Cultural Values on Prophylactic DHP Adherence and Malaria Incidence among Pregnant Women in Papua, Indonesia}, journal = {Pharmacognosy Journal}, volume = {18}, year = {2026}, month = {June 2026}, pages = {208-215}, type = {Original Article}, chapter = {208}, abstract = {

Background: Malaria during pregnancy remains a major public health concern in Papua, Indonesia, with significant maternal and neonatal consequences. Although dihydroartemisinin{\textendash}piperaquine (DHP) is effective as prophylaxis, adherence remains suboptimal. Culturally grounded, family-based approaches may improve adherence. Objective: To evaluate the effectiveness of a family empowerment intervention based on Arui Sai cultural values on DHP adherence and malaria incidence among pregnant women. Methods: A quasiexperimental study with a pretest{\textendash}posttest control group design was conducted in Kepulauan Yapen Regency from March to December 2025. A total of 184 pregnant women (92 in the intervention group; 92 in the control group) were analyzed. The intervention involved family empowerment through educational modules, home visits, and family engagement, whereas the control group received standard antenatal care. The outcomes included DHP adherence (>=80\%) and malaria incidence during a five-month follow-up period. Data were analyzed using chi-square tests and logistic regression. Results: DHP adherence was significantly greater in the intervention group (95.7\% vs. 63.0\%; OR=12.90; 95\%CI: 4.35{\textendash}38.27; p\<0.001). In the multivariable analysis, the intervention remained a significant predictor (adjusted OR=13.73; 95\%CI: 4.42{\textendash}42.65; p\<0.001). The incidence of malaria was lower in the intervention group according to the results of the bivariate analysis (7.6\% vs. 20.7\%; RR=0.37; 95\%CI: 0.16{\textendash}0.83; p=0.020) but was not significantly different after adjustment (adjusted OR=0.42; 95\%CI: 0.15{\textendash}1.17; p=0.098). Living near vector breeding sites was an independent predictor (adjusted OR=4.09; p=0.010). Conclusion: Family empowerment based on Arui Sai cultural values significantly improves DHP adherence. Integration with environmental risk control is necessary for malaria prevention in high-endemic settings.

}, keywords = {Arui Sai, cultural intervention, DHP adherence, Malaria during pregnancy, prophylaxis, quasiexperimental study}, doi = {10.5530/pj.2026.18.135}, author = {Silas Mabui and Hasanuddin Ishak and Ridwan Thaha and Syamsuar S and Firdaus Hamid and Andi Muhammad Akhmar and Muhamad Sahiddin and Anwar Mallongi} } @article {2265, title = {Determinants of Adverse Birth Outcomes in Ambon, Indonesia: A Case-Control Study}, journal = {Pharmacognosy Journal}, volume = {16}, year = {2024}, month = {April 2024}, pages = {410-414}, type = {Research Article}, chapter = {410}, abstract = {

Background: Globally, adverse birth outcomes were still high, especially in low and middle-income countries like Indonesia. Stillbirth, preterm birth (PTB), low birth weight (LBW), and first-minute birth asphyxia are some of the adverse birth outcomes. The incidence of adverse birth in Ambon is quite high but never been any research about determinants of adverse birth outcomes. Objective: This study aims to examine the determinants of adverse birth outcomes and identify the main modifiable risk factors in Ambon. Method: This retrospective case-control study included all birth outcomes in August and September 2023 in Ambon, Indonesia. A total of 165 birth outcomes (55 cases and 110 controls) with complete information in Puskesmas and Posyandu were included in the analysis. The Chi-square test and regression analyses were applied to evaluate the association between variables. Result: This study showed the impact of pregnant women{\textquoteright}s age, parity, passive smoking, ANC examination, and ANC counseling on birth outcomes. There are differences in maternal age (p=0.006; 95\% CI: 1.22-6.11), parity (p=0.001; 95\% CI: 1.52-8.51), passive smokers (p=0.004; 95\% CI: 1.37-8.99, ANC examination (p=0.02; 95\% CI: 1.08-5.01) and ANC counseling (p=0.002; 95\% CI: 1.44-8.67) between case and control groups. Conclusion: Maternal age (<= 20 and \>35 years old), parity (one and >= 5), passive smokers, ANC examination not according to standard, and ANC counseling without a husband were associated with a high risk of all adverse birth outcomes.

}, doi = {10.5530/pj.2024.16.64}, author = {Magdalena Paunno and Ridwan Amiruddin and Masni and Mardiana Ahmad and Bertha Jean Que and Ridwan Thaha and Sudirman Nasir and Anwar Mallongi} }