@article {2176, title = {Emilia Sonchifolia-A Critical and Comprehensive Review of its Diverse Medicinal Potential and Future as Therapeutic}, journal = {Pharmacognosy Journal}, volume = {15}, year = {2023}, month = {December 2023}, pages = {1143-1149}, type = {Research Article}, chapter = {1143}, abstract = {

Emilia sonchifolia (L.) DC, it belongs to the family Asteraceae or Compositae, is conventionally used in ethnomedicine, and acquires various medicinal properties. This plant has been regarded as one of the widespread traditional vegetable salads in Malaysia, Bangladesh, and India. In addendum to its avail as a vegetable, the plant has been documented with several medicinal benefits in the extravagance of night blindness, epilepsy, malaria, asthma, burns, breast abscesses, and inflammatory diseases. On scrutinization of their pharmacological properties, it has been revealed that they possess numerous notable biological properties such as antimicrobial, analgesic, anti-inflammatory, antioxidant, hepatoprotective, antianxiety, and anticataract, as well as anticonvulsant activities. Concrete evidence suggests the presence of potential phytochemicals in this plant with a wide range of unknown applications. In this current review, we discuss the phytochemicals present in the plant Emilia sonchifolia and emphasize the therapeutic and pharmacological activities reported so far concerning this plant.

}, keywords = {Anti-inflammatory, Anti-tumour, Emilia sonchifolia, Medicinal plant, Phytochemicals}, doi = {10.5530/pj.2023.15.208}, author = {Sardar Hussain and Komal KP and Guruvayoorappan C} } @article {1266, title = {Grapes and their Bioactive Compounds: Role in Health Management Through Modulating Various Biological Activities}, journal = {Pharmacognosy Journal}, volume = {12}, year = {2020}, month = {September 2020}, pages = {1455-1462}, type = {Review Article}, chapter = {1455}, abstract = {

Grape is one of the important plant and its implication in health management has been proven. Grapes are used in the production of grape juice, food products and in other form. The fruits leaves and seeds of the plant are confirmed its role in diseases management based on in vivo and in vitro study. Leaves, fruits and seeds of grape are rich source of bioactive compounds and such compound play role in diseases cure and management. Grapes leaves, fruits and seeds shows therapeutic implications as antioxidant, anti-inflammatory, anti-diabetic, hepatoprotective effect and antimicrobial. Grapes leave, fruit and seed and their active compounds play significant role in inhibition of cancer. Its bioactive compound has designated its role in tumour management through modulating genes activity. This review comprehensively summarizes the role of grapes fruits, seeds and leaves in diseases management through modulating different biological activities based on in vivo and in vitro study.

}, keywords = {Anti-inflammatory, Anti-tumour, Antioxidant, Proanthocyanidins, Vitis vinifera}, doi = {10.5530/pj.2020.12.200}, author = {Saleh A Almatroodi and Ahmad Almatroudi and Mohammed A Alsahli and Arshad Husain Rahman} } @article {854, title = {Assessment of Phyto-Constituents by GC-MS and Anti-Tumour Activity of Garlic Grown in Different Altitude: A Comparative Study}, journal = {Pharmacognosy Journal}, volume = {11}, year = {2019}, month = {February 2019}, pages = {350-354}, type = {Original Article}, chapter = {350}, abstract = {

Background: Garlic (Allium sativum L.) is most important spice containing highest sources of total phenolic compounds. It has been used as a component of traditional and modern medicine. Pharmacological properties of garlic is mainly depend on its phyto-constituents content, which varies between geographical regions. The aim of this study was to evaluate and compare the phyto-constituents content of garlic sample collected from high ranges of Idukki (Kanthallur) with that of Tamil Nadu (Mettupalayam market) garlic sample. Materials and Methods: garlic clove sample were collected from high ranges of kanthallur region (GSK) and Mettupalayam region (GSM). The garlic oil was extracted from the collected garlic sample by solvent extraction method. The phytochemical study of extracted garlic oil were conducted using standard methods of analysis and subjected GC-MS analysis. Further, the extracted oil samples were studied for their anti-tumour activity against Dalton Lymphoma Cell Lines (DLA) in an in vitro model. Results: The obtained results revealed that garlic oil of GSK showed highest percentage of yield of oil (1.1\%) than garlic oil of GSM (0.6\%). The phytochemical screening of GSK indicated the presence of alkaloids and flavonoid, whereas GSM showed presence of alkaloids only. GC-MS analysis of garlic oil study indicated that garlic oil of GSK was found to have eugenol as a novel source compared with garlic oil of GSM. Garlic oil of GSK showed significant anti-tumour activity against DLA cells, compared with garlic oil of GSM. Conclusion: Garlic oil of GSK exhibited potential anti-tumour activity against DLA cells due to presence of eugenol compound as novel source.

}, keywords = {Anti-tumour, Garlic oil, GC-MS, MTT, Phyto-constituents}, doi = {10.5530/pj.2019.11.52}, author = {Susha Antony and Kunnambath Krishna Kumar and Jalaja Sudhi Menon} }