@article {1404, title = {The Anthelmintic Activity of Cawat Anuman (Bauhinia Sp.) Leaves Against Ascaridia galli Worms}, journal = {Pharmacognosy Journal}, volume = {13}, year = {2021}, month = {May 2021}, pages = {626-630}, type = {Original Article}, chapter = {626}, abstract = {

Background: Traditionally, the people in Anik Hamlet usually use the Bauhinia sp. leaves as anthelimintic. Objective: The research was conducted to observe the anthelmintic activity of the ethanol extract of cawat anuman (Bauhinia sp.) leaves against Ascaridia galli by in vitro procedure. Methods: Group I was treated with NaCl 0.9\% as the negative control, also group II and III were treated with cawat anuman leaves ethanol extract at dose of 25 mg/ml and 50 mg/ ml respectively, and group IV was treated with mebendazole at dose 5 mg/ml as the positive control. Results: Compared to the negative control, the ethanol extract of cawat anuman leaves has activity as an anthelmintic (p\<0.05), moreover the potency of leaves extract at dose 50 mg/ml as anthelmintic against Ascaridia galli as strong as mebendazole at dose 5 mg/ml (p\>0.05). Conclusion: It concluded that the ethanol extract of cawat anuman leaves at dose 50 mg/ml has anthelmintic potency as strong as mebendazole 5 mg/ml.

}, keywords = {Anthelmintic activity, Ascaridia galli, Bauhinia sp. Leaves}, doi = {10.5530/pj.2021.13.79}, author = {Ruqiah Ganda Putri Panjaitan and Ela Elisa and Eko Sri Wahyuni} } @article {1044, title = {Anthelmintic Activity of Millettia pachycarpa Root Bark Extract on an Intestinal Roundworm, Ascaridia galli}, journal = {Pharmacognosy Journal}, volume = {11}, year = {2019}, month = {November 2019}, pages = {1428-1433}, type = {Original Article}, chapter = {1428}, abstract = {

Background: Millettia pachycarpa Benth. is member of the family Fabaceae and is a wellknown traditional medicinal plant used for different health conditions. Its roots and seeds are rich in bioactive compounds such as chalcones, isoflavones and rotenoids, which are attributed to the anticancer, antiparasitic and insecticidal properties of the plant. In Mizo traditional medicine, the root bark is also used for parasitic infections. Objective: The study was designed to understand the anthelmintic efficacy and effects of M. pachycarpa on an intestinal roundworm, Ascaridia galli. Materials and Methods: The methanolic extract of the root bark was prepared and survival test was performed against A. galli. The structural effects were studied using scanning electron microscopy and histological preparations. Results: The roundworm showed extensive structural changes and damages. The cuticle showed extensive shrinkage and cracks. Lacerations and scars distorted the fine transverse rings. The mouthparts collapsed with shrunken lips and degenerated denticles. Internal tissues such as musculature and reproductive organs were also impaired. Conclusion: The findings indicate that the plant extract is effective against parasitic roundworms.

}, keywords = {Ascaridia galli, Cuticle, microscopy, Millettia pachycarpa, Roundworm}, doi = {10.5530/pj.2019.11.221}, author = {Kholhring Lalchhandama} }