@article {1976, title = {Tectona Grandis Leaves: Determination of Total Flavonoid Content, Phenolic Content, Characterization of the Leaves, and Compound Identification in GC-MS}, journal = {Pharmacognosy Journal}, volume = {15}, year = {2023}, month = {March 2023}, pages = {165-170}, type = {Research Article}, chapter = {165}, abstract = {

Nowadays, traditional plant study has grown in importance as their use has been increased. Tectona grandis (teak) is one of several plants that have been studied for its phytochemical and pharmacological properties. This plant includes a number of secondary metabolites, which may explain its diverse pharmacological properties. Although teak leaf compounds have been examined in the past, there is still little information on the diversity of teak leaf compounds. As a result, we are employing several methodologies to determine the total flavonoids content, phenolic content, water extractable matter, ethanol extractable matter, total ash content, and other component analysis of teak leaves. We found that the average of total flavonoid content in the teak leaves is about 3.93 {\textpm} 0.008\%w/w, while the average total phenolic concentration in teak leaves is about 4.3{\textpm}0.15\%w/w. The Gas Chromatography- Mass Spectrometry GC-MS study of the methanol extract of T. grandis leaves also found twenty-three active chemical compounds (phytochemical components)

}, keywords = {Ash content, Flavonoids content, GC-MS., Moisture content, Phenolic content, Teak, Tectona grandis, Water content}, doi = {10.5530/pj.2023.15.24}, author = {Pepi Budianto and Suroto Suroto and Brian Wasita and Diah Kurnia Mirawati} } @article {1150, title = {In-vitro Antioxidant and In-Vivo Hepatoprotective Activity of Ethenolic Extract of Tectona grandis Bark Against CCl4 Induced Liver Injury in Rats}, journal = {Pharmacognosy Journal}, volume = {12}, year = {2020}, month = {May 2020}, pages = {598-602}, type = {Research Article}, chapter = {598}, abstract = {

Objectives: The systematic screening of Tectona grandis bark with the purpose of discovering new bioactive compounds as a hepatoprotective agent and to establish the scientific basis for the therapeutic actions of traditional plant medicines. Methods: Tectona grandis bark ethenolic extract was studied for the hepatoprotective activity against CCl4 induced liver injury in rats. Serum enzymes level, total bilirubin and histopathological study of liver were performed. This extract{\textquoteright}s DPPH radical scavenging potential was also studied. Results: Oral administration of ethenolic extract of Tectona grandis bark (200 mg/kg) exhibited significant reduction (p\<0.05) in CCl4-induced increased levels of SGPT, SGOT, ALP and bilirubin (Total) concentration. Treatment with Liv 52 syrup also reversed the hepatotoxicity significantly (p\<0.05). Histopathological studies also provided supportive evidence for biochemical analysis. This extract also showed better activity in quenching DPPH radical. Conclusion: Tectona grandis bark ethenolic extract shown to have hepatoprotective and antioxidant action due to presence of quinones and tannin like phytoconstituents.

}, keywords = {Antioxidant, CCL4 induced hepatopathy, Hepatotoxicity, Histopathology, Quinones, Tectona grandis}, doi = {10.5530/pj.2020.12.89 }, author = {Rajkumar S Bagali and Sunil S Jalalpure and SS Patil} }