@article {1171, title = {Effect of Solvent on the Phytochemical Extraction and GC-MS Analysis of Gymnema sylvestre}, journal = {Pharmacognosy Journal}, volume = {12}, year = {2020}, month = {June 2020}, pages = {749-761}, type = {Research Article}, chapter = {749}, abstract = {

The medicinal plant Gymnema sylvestre found in the Indian subcontinent and Srilanka is known for its anti-diabetic, diuretic, anti-obesity, anti-cancer, antimicrobial, anti-inflammatory properties. The current study is focused on the phyto compound extraction efficiency of different solvents like ethanol, methanol, ethyl acetate, hexane, benzene and chloroform by gas chromatography{\textendash}mass spectrometry analysis of Gymenma sylvestre. From the results, it is concluded that G. sylvestre leaves extracts contains more than 38 phyto compounds with natural antioxidants potential. Further analysis of the extract will help in identifying the effective compounds which can be of potent use in the pharmacological field.

}, keywords = {Chromatography, Cold maceration, Gymnema sylvestre, Medicinal plants, plant constituents}, doi = {10.5530/pj.2020.12.108}, author = {Sundarapandian Subramanian and Mohammed Junaid Hussain Dowlath and Sathish Kumar Karuppannan and Saravanan M and Kantha Devi Arunachalam} } @article {1240, title = {Effect of Solvents on Phytochemical Composition and Antioxidant Activity of Cardiospermum halicacabum (L.) Extracts}, journal = {Pharmacognosy Journal}, volume = {12}, year = {2020}, month = {September 2020}, pages = {1241-1251}, type = {Original Article}, chapter = {1241}, abstract = {

Background: Cardiospermum halicacabum (C. halicacabum) is a common medicinal herb found in India and other Asian countries. It has various medicinal properties such as antimicrobial, pain relief, antibiotics, anti-inflammatory, antioxidants, anticancer etc. It is commonly used for treating diabetes, arthritis, limbs stiffness, rheumatism, lumbago, earache, fever. Type of solvent and polarity intensively affects the antioxidant activity of the extracts due to the solubility of the phytocompounds such as polyphenols and flavonoids in various solvents. Materials and Methods: In this study, different solvents like, ethanol, methanol, chloroform and petroleum ether were used for the extraction of C. halicacabum. Cold maceration method was followed for extraction. The crude extracts were screened preliminary and then confirmed using Fourier transform-infrared spectroscopy analysis. Gas chromatography-mass spectrometry was used to determine the chemical composition of each extract. The DPPH (2,2-diphenyl- 1-picrylhydrazyl) method was used for the evaluation of the antioxidant activity of different crude extracts of C. halicacabum. Results: The results showed that there is significant influence of solvent type in preserving various phytocompounds of the C. halicacabum leaves extract. The evaluation of the antioxidant capacity of different crude extracts was in the order of ethanol \> methanol \> petroleum ether \> chloroform extract.

}, keywords = {Cardiospermum halicacabum, Cold maceration, DPPH, GC-MS, Medicinal plants, Phytochemicals, Radical scavenging activity}, doi = {10.5530/pj.2020.12.173}, author = {Mohammed Junaid Hussain Dowlath and Sathish Kumar Karuppannan and Darul Raiyaan GI and Mohamed Khalith SB and Sundarapandian Subramanian and Kantha Deivi Arunachalam} }