@article {1323, title = {A New Ursane-Type Triterpene from the Fermented Shallot Allium Ascalonicum}, journal = {Pharmacognosy Journal}, volume = {13}, year = {2021}, month = {January 2021}, pages = {01-07}, type = {Original Article}, chapter = {01}, abstract = {

3,24-acetonideclethric acid (1), a new ursane-type triterpene, and four known compounds including ursolic acid (2), randiasaponin IV (3), ilekudinoside W (4) and (25S)-1β,3β,24β- trihydroxyspirost-5-en 1-O-α-L-rhamnopyranosyl-(1{\textrightarrow}2)- α-L-arabinopyranoside (5), and were isolated from the fermented shallot Allium ascalonicum. Their structures were determined by analysis of HR-ESI-MS, NMR spectral data, as well as comparison with those reported in the literature. All of the saponins (3-5) exhibited antimicrobial activity against three strains Staphylococcus aureus, Escherichia coli, and Candida albicans with IC50 values in the range from 89.49 {\textpm} 2.24 to 95.71 {\textpm} 3.86 μM.

}, keywords = {24-Acetonideclethric acid, 3, Allium ascalonicum, Antimicrobial activity, Saponin}, doi = {10.5530/pj.2021.13.1}, author = {Nguyen Van Chuyen and Nguyen Hong Son and Pham Van Hien and Dang Truong Giang and Ho Ba Ngoc Minh and Ngo Thi Tuyet Mai and Chu Van Men and Ho Anh Son and Vu Binh Duong} }