@article {2550, title = {Association Between Contraceptive Use and Pap Smear Findings in PKK Women in Bendul Merisi Surabaya}, journal = {Pharmacognosy Journal}, volume = {17}, year = {2025}, month = {September 2025}, pages = {642-643}, type = {Original Article}, chapter = {642}, abstract = {

Background: Cervical cancer remains a major health burden for women worldwide. Pap smear is a widely used screening tool, while contraceptive use, particularly hormonal methods, has been debated as a potential risk factor for cervical lesions. Objective: This study aimed to investigate the association between contraceptive use and Pap smear findings among members of the Family Welfare Movement (PKK) in Bendul Merisi, Surabaya. Methods: A cross-sectional study was conducted involving 64 respondents selected through purposive sampling. Data were collected using questionnaires and Pap smear results. Statistical analysis was performed using contingency coefficient tests. Results: The study revealed a significant association between contraceptive use and Pap smear results (p = 0.001). Different types and duration of contraceptive use were significantly related to cytological outcomes, with hormonal methods showing a stronger association with abnormal findings such as LSIL (Low-grade Squamous Intraepithelial Lesion). Conclusions: Contraceptive use, especially hormonal methods with longer duration, influences Pap smear findings, highlighting the need for regular cervical cancer screening among women using hormonal contraception

}, keywords = {Cervical cancer, Contraceptives, Cytology, Pap Smear, Uterine Cervix}, doi = {10.5530/pj.2025.17.80}, author = {Nefertiti EP and Sudiarta KE and Redemptus Y and Biutifasari V} } @article {2311, title = {Eosinophil Cell and Mass Appearance in Atypical Mycobacterium Infection of Lymphadenitis}, journal = {Pharmacognosy Journal}, volume = {16}, year = {2024}, month = {June 2024}, pages = {664-667}, type = {Research Article}, chapter = {664}, abstract = {

Introduction: Atypical mycobacterium (ATM) is acid fast bacilli not including tuberculosis and may had opportunistic feature in environment either in air or soil. While symptoms of ATM infection may look similar with typical tuberculosis, these specific group of disease were harder to treat and would necessitate longer antibiotics consumption. While PCR may readily available to detect ATM, anatomical pathology method such as biopsy may be a cheaper alternative in low-resource settings to differentiate between atypical and typical mycobacterium infection. Aim: To analyze correlation between eosinophil cells and eosinophil mass with ATM in lymphadenopathy patient. Methods: This study is an analytical observational study with cross-sectional design which aimed to review diagnostic abilities of eosinophil cell and mass to detect ATM. Patient would undergo both PCR as gold standard of diagnosis and cytology biopsy aspiration as comparative diagnostic modalities. Data would be presented from SPSS v. 25. Results: We collected 70 subjects that fulfill inclusion and exclusion criteria. Most samples were dominated by female in relatively young age. There are 37 patients with ATM in which 75,7\% patients cytology result shown expression of eosinophil cells and 71,4\% patients shown eosinophilic mass. Chi-square test revealed that statistical significance existed between eosinophilic cells with ATM. However, such statistical significance was not found between eosinophilic mass and ATM. Conclusion: Eosinophilic cell can be used as alternative diagnostic modalities in diagnosing ATM. Further studies should further examine pathophysiological correlations and diagnostic power.

}, keywords = {Atypical mycobacterium, Cytology, Eosinophil}, doi = {10.5530/pj.2024.16.105}, author = {Neni Wahyu Hastuti and Delfitri Munir and Reno Keumalazia Kamarlis and Bintang Yinke Magdalena Sinag and Adang Bachtiar and Farhat and Amira Permatasari Tarigan and Delyuzar} }