@article {844, title = {Preparation and Evaluation of Nutraceutical Product Mixture of Seeds of Cucumis melo, Punica granatum, Linum usitatissimum, for Antioxidant, Prebiotic and Nutraceutical Potential}, journal = {Pharmacognosy Journal}, volume = {11}, year = {2019}, month = {February 2019}, pages = {383-387}, type = {Original Article}, chapter = {383}, abstract = {

Introduction: Pharmaceutical formulation scientists are currently developing new materials and formulations which vividly include Nutraceuticals. {\textquotedblleft}Nutraceutical{\textquotedblright} is a substance that is considered a food or part of a food processed as pharmaceutical, which provides medical or health benefits, encompassing prevention and treatment of diseases. Materials and Methods: Under this research Nutraceutical Product Mixture was prepared using seeds of Cucumis melo, Punica granatum and Linum usitatissimum. Individually these three seeds are reported to contain rich nutrients along with antioxidants, probiotic soluble fibres and thus the mixture of three increased this potential. Individual seed and the mixture was evaluated by In- vitro and In-vivo methods for Nutraceutical Potential. Results: Proximate analysis of the mixture showed rich nutrient content and provided good combination of nutrients. Individual seed powder as well as mixture was tested for prebiotic potential using lactobacilli culture, which showed positive results. Each seed powder as well as mixture was tested for antioxidant potential using DPPH free radical scavenging assay, with promising results. It{\textquoteright}s in- vivo effect was studied using Wistar albino rat as animal model. This study involved haemogram and lipid profile determination which showed certain promising results. The powder mixture was developed into two products namely capsule and health drink powder formula. Conclusion: The nutraceutical powder mixture of seeds of Cucumis melo, Punica granatum and Linum usitatissimum could be a promising product with antioxidant, prebiotic and nutraceutical potential for diabetic and cardiac patients where oxidative stress is a major underlying cause.

}, keywords = {Antioxidant potential, Cucumis melo, Linum usitatissimum, Nutraceutical potential, Nutraceuticals, Prebiotic potential, Proximate Analysis, Punica granatum}, doi = {10.5530/pj.2019.11.59}, author = {Meera Chandradatt Singh and Kishore N. Gujar} } @article {178, title = {GC- MS Analysis of Mussaenda roxburghii Hk.f.: A Folk Food Plant Used Among Tribes Of Arunachal Pradesh, India.}, journal = {Pharmacognosy Journal}, volume = {8}, year = {2016}, month = {June/2016}, pages = {395-398}, type = {Original Article}, chapter = {395}, abstract = {

Introduction: Mussaenda roxhburgii Hk.f. shoot is widely used as folk food among the tribal people of Arunachal Pradesh. This study was carried out to establish the phytoconstituents of Mussaenda roxburghii shoot. Methods: Fresh shoot were collected from Mone forest of East Siang district of Arunachal Pradesh and identified by the corresponding author himself. The samples were shade dried and pulverized to powder using a mechanical grinder. 500 g powder of the sample was soaked in ethanol for 72 hours with intermittent shaking then filtered through Whatmann No. 41 filter paper and concentrated under reduced pressure at 40\°C by using rotary evaporator to obtain a viscous semi solid extract. Gas-Chromatography Mass Specrometry (GC-MS) analysis of the ethanol extracts was carried out in Shimadzu GCMS-QP-2010 plus system. The identification of compounds was performed by comparing their mass spectra with data from NIST 11 (National Institute of Standards and Technology, US) and WILEY 8. Results: The GCMS chromatogram of Mussaenda roxburghii shoot ethanolic extract gave forty nine phytochemical compounds. The most prevailing compounds were hydrocoumarin with 13.6\%, hexadeconoic acid, 2-hexadecen-1-ol, 3, 7, 11, 15 tetramethyl [R-[R-) with 17.52\%, ethyl ester with 6.24\% and Vitamin E with 2.8\%. The study gave some compounds with biological interest like gamma tocopherol, Vitamin E, Neophytadiene, Squalene etc. which have been reported to be Antitumur, Antiinflammatory, Antiaging, antidiabetic, anti-inflammatory, Antipyretic, perfume, pesticide and sunscreen.

}, keywords = {Folk Food, GC-MS, Hydrocoumarin., Mussaenda species, Nutraceuticals, Tribal people}, doi = {10.5530/pj.2016.4.14}, author = {Temin Payum} }