02177nas a2200217   4500008004100000245019200041210006900233260001700302300001400319490000700333520142400340653001301764653002301777653001501800653001601815653002601831100002501857700001601882700002501898856003601923       2019                        eng d00aThe Effect of Coriander Ethanol Extract (Coriandrum sativum L.) Against Phagocytosis Activity and Capacity of the Macrophage Cells and the Percentage of Leukocyte Cells in White Male Mice0 aEffect of Coriander Ethanol Extract Coriandrum sativum L Against  cOctober 2019  a1290-12980 v113 a<p class="rtejustify">Coriander has long been used by humans as a traditional drug and to enhances the taste of foods. This study aims to know the effects of coriander ethanol extract against phagocytosis activity and capacity of the macrophage cells and the percentage of leukocytes. The test animals used were white male mice which divided into 4 groups and each group consists of 5 mice. The first group (control) was given with 0.5% Na CMC suspension. The second, the third, and the fourth groups were given with coriander extract each with doses of 100 mg/kg, 140 mg/kg and 200 mg/kg orally for 7 days long. On the 8th day, the mice were induced by <em>Staphylococcus aureus </em>to help their immune system. The results showed that the administration of coriander extract at doses of 100, 140 and 200 mg/kg can increase the phagocytic activity of macrophages by 44.6%; 54.2%; and 60.2% each, while the phagocytic capacity replaces the results of 95.8; 104.4; and 126 cells. The total number of leukocytes showed were 5210, 6190, and 7310 /μL blood. In the number of leukocyte cells, the amount of coriander extract can reduce the number of neutrophil and monocyte cell segments. The conclusion of this study regarding coriander ethanol extract at doses of 100, 140 and 200 mg/kg can increase phagocytosis activity and capacity of the macrophage cells and the total leukocyte cell counts in male white mice.</p>
10aActivity10aCoriandrum sativum10aLeukocytes10aMacrophages10aPhagocytosis capacity1 aDillasamola, Dwisari1 aAldi, Yufri1 aKolobinti, Marselani  uhttps://phcogj.com/article/1012