01995nas a2200205 4500008004100000245016100041210006900202260001500271300001200286490000700298520131300305653001601618653001301634653002901647653001401676100002601690700002101716700001601737856003601753 2020 eng d00aArginase Inhibitory, Antioxidant Activity, Total Phenolic Content and Total Flavonoid Content of Ethyl Acetate Extract of Caesalpiniaturtuosa Roxb Stem Bark0 aArginase Inhibitory Antioxidant Activity Total Phenolic Content  cMarch 2020 a227-2310 v123 a

Objective: The purpose of this study is to investigate arginase inhibition, antioxidant activity, total phenolic content and total flavonoid content of ethyl acetate extract of Caesalpiniaturtuosa Roxb. Material and method: stem bark of Caesalpiniaturtuosa Roxb was extracted using hexane, ethyl acetate and methanol subsequently. The ethyl acetate extract was fractioned. Then, the fractions were subjected to arginase inhibition, antioxidant activity, total phenolic content and total flavonoid assay. Correlation was considered by statistical analysis. Result: Out of eight fractions, two fractions have no activity. Two fractions (3 and 6) have strong activity in arginase with inhibition 90.72 % and 91.41% respectively. Fraction 3 and 6 have strong antioxidant activity with IC50 25.98 μg/mL and 48.01 μg/mL respectively. Statistical analysis shows arginase inhibitor activity was not related with antioxidant activity, total phenolic content and total flavonoid content in this plant. Conclusion: Activity in arginase inhibition of fraction from ethyl acetate extract of Caesalpiniaturtuosa Roxb are not related to antioxidant, total phenolic and flavonoid content.

10aAntioxidant10aArginase10aCaesalpiniaturtuosa Roxb10aFlavonoid1 aAtikasari, Nadilla, N1 aHanafi, Muhammad1 aElya, Berna uhttps://phcogj.com/article/1096