01958nas a2200217 4500008004100000245010400041210006900145260001900214300001400233490000700247520129700254653001701551653002101568653000901589653002001598100003001618700001901648700001801667700001901685856003601704 2020 eng d00aTotal Phenolic Content and Antioxidant Activity of Different Extracts of Cordia sebestena L. Leaves0 aTotal Phenolic Content and Antioxidant Activity of Different Ext cSeptember 2020 a1311-13160 v123 a

Background: Cordia sebestena L. (Boraginaceae) wildly planted in Jakarta, Indonesia. The secondary metabolites of plants have biological and pharmacological activities, such as antioxidant. The antioxidant activity of plants might be due to their phenolic compounds. Objective: To determine the total phenolic content and evaluate the antioxidant activity of C. sebestena leaves extracts (n-hexane, dichloromethane, ethyl acetate, and 70% ethanol). Materials and Methods: The total phenolic content was determined using spectrophotometric methods with a Folin-Ciocalteu reagent. The antioxidant activity of the extracts was determined by its ability to inhibit DPPH radicals through IC50 values (ppm). Results: The highest total phenolic content (167.61 ± 0.56 mg GAE/g) and best antioxidant activity (31.41 ppm) were found in 70% ethanol extract of C. sebestena compared to other extracts (ethyl acetate > dichloromethane > n-hexane). Conclusion: The C. sebestena leaves have a good potential as a source of natural antioxidant, and further research, is recommended to evaluate the antioxidant activity using another method.

10aBoraginaceae10aCordia sebestena10aDPPH10aFolin-Ciocalteu1 aHikmawanti, Ni, Putu Ermi1 aHanani, Endang1 aSapitri, Yuni1 aNingrum, Wulan uhttps://phcogj.com/article/1247