01916nas a2200229 4500008004100000245011900041210006900160260001500229300001200244490000700256520121100263653002801474653002101502653002001523653001401543100001501557700001401572700002601586700001901612700001901631856003601650 2021 eng d00aAnti-Cancer Activity of Cayratia Auriculata Ethanolic Extracts Against Cancer Cell Line A549 An In Vitro Analysis0 aAntiCancer Activity of Cayratia Auriculata Ethanolic Extracts Ag cMarch 2021 a495-4990 v133 a

Background: The purpose of this study was to evaluate the anticancer activity of ethanolic cayratia auriculata extracts using the A549 cell line MTT assay. Materials and Methods: Using Soxhlet apparatus, ethanolic extracts from cayratia auriculata were prepared. The cancer cells were exposed to 12.5, 25, 50 , 100 , 150, 200 μg / mL and incubated for 24 h at different concentrations. Compared with control, C. auriculata exhibited a cytotoxic effect. Results: At 150 and 200μg / ml concentrations, with 61 percent and 73.7 percent respectively, the highest cytotoxicity was identified. The findings show that cytotoxicity is directly proportionate to the concentration of the extract. IC50 of the ethanolic extract value of C. auriculata was found to be 102.9μg / ml against the A549 cell line. Conclusion: In the present analysis, C.auriculata ethanolic extract was shown to be a strong suppressant for cell division and proliferation. As for anti-tumor medicine, it can be a new source and can be effectively used as an immunological anti-malignant compound.

10aActivity against cancer10aCell line cancer10aEthanol Extract10aMTT Assay1 aLalitha, S1 aAnusha, D1 aMurkunde, Yogeshkumar1 aDevanand, Viji1 aMaheshkumar, K uhttps://phcogj.com/article/1386