02623nas a2200205 4500008004100000245010700041210006900148260001500217300001200232490000700244520197500251653001802226653001602244653002102260653002002281100002702301700002702328700002602355856003602381 2021 eng d00aAntibacterial and Antioxidant Activities of Ethanol Extracts of Some Plants Selected from South Jordan0 aAntibacterial and Antioxidant Activities of Ethanol Extracts of  cMarch 2021 a528-5340 v133 a

Three Jordanian medicinal plants; Peganum harmala (P. harmala), Geropogon hybridus (G. hybridus), and Salvia officinalis (S. officinalis) were selected from Al-karak region in order to investigate their antibacterial and antioxidant activities. The crude extract yield of all used plants were varied from 10.6% in Salvia officinalis and 15.6% in P. harmala, to 18 % in G. hybridus. The antibacterial activity of these plants was carried out on four bacterial strain (S. aureus, E.coli, E. aerogenes and B. subtilis). These plant ethanol extracts have effects on the gram positive strains and gram negative bacteria except S. officinalis did not show activity against E. Coli. The minimal inhibition concentration (MIC) of P. harmala S. officinalis and G. hybridus (MIC) ranged from 125 μg/ml to 500 μg/ml. The ethanol crude extract of G. hybridus gave 10 fractions using TLC method, fraction 1,3 and 10 exhibited antibacterial activity against all bacterial strains. Their total phenolic contents were evaluated; the highest total phenol content was observed in G. hybridus with 410 mgGAE/g plant extract followed by P. harmala and S. officinalis with 305 and 203.7 mg/g plant extract, respectively. The antioxidant activity was estimated by using DPPH method. The highest antioxidant activity was obtained with G. hybridus extract and found to be 0.89 mg Trolox/g plant extract. The lowest antioxidant activity was obtained with S. officinalis which was 0.53 mg Trolox/g plant extract. The lowest IC50 (highest antioxidant activity) was observed in G. hybridus with 0.83 mg/ml. Intermediate effect observed in P. harmala with IC50 1.1 mg/ml. The lowest antioxidant activity was obtained in S. officinalis with IC50 1.38 mg/ml.

10aAntibacterial10aAntioxidant10aEthanol extracts10aPeganum harmala1 aani, Waleed, Khaled Al1 aAlqudah, Ali, Abdallah1 aTarawneh, Khaled., A. uhttps://phcogj.com/article/1390