01384nas a2200253 4500008004100000245008800041210006900129260001300198300001200211490000700223520071800230653001500948653001600963653000900979653002100988653003801009100002201047700000501069700000501074700000501079700000501084700000501089856003601094 2021 eng d00aEvaluation of Antioxidant and Anticancer Activity of Myristica fragrans Houtt. Bark0 aEvaluation of Antioxidant and Anticancer Activity of Myristica f cMay 2021 a780-7860 v133 a
This study aims to evaluate the antioxidant and anticancer activity of secondary metabolite compounds from Myristica fragrans Houtt. (nutmeg) bark using n-hexane extract based on DPPH radical scavenging and microculture tetrazolium salt (MTT) assay. The chemical structural analysis using NMR, FTIR, and LC-MS spectroscopy confirmed and identified the structure of isolated compound namely (2E)-5(2z.4E)-hexa-2,4,-dio-zyl)-2propylcyclohexanol (C18H30O4) for the first time which is corresponding for the excellent antioxidant and anticancer activity against MCF-7 cell lines with the IC50 value of 99.76 and 10.75 ppm, respectively.
10aAnticancer10aAntioxidant10aBark10an-hexane extract10aNutmeg (Myristica fragrans Houtt)1 aGinting, Binawati1 a1 a1 a1 a1 a uhttps://phcogj.com/article/1425