01946nas a2200229 4500008004100000245011800041210006900159260001300228300001200241490000700253520124900260653001501509653001301524653001401537653002001551100001901571700002401590700001701614700002601631700002301657856003601680 2021 eng d00aGraptophyllum pictum (L.) Griff. (Syn: Justicia picta Linn.) and its Effectiveness: A Well-Known Indonesian Plant0 aGraptophyllum pictum L Griff Syn Justicia picta Linn and its Eff cMay 2021 a835-8380 v133 a

Graptophyllum pictum (L.) Griff., a shrubby stove plant, has been used traditionally to treat various diseases. This review summarizes the up-to-date data about its phytochemistry and pharmacological properties and provides a perspective and direction for future research. The phytochemical analysis of G. pictum revealed the presence of flavonoids, steroids, glycoside, tannins, saponin, chlorophyll, nontoxic alkaloid, and anthocyanin. Meanwhile, the pharmacological analysis revealed that this plant possessed various activities such as antimicrobial, immunomodulatory, antioxidant, anti-inflammation, anti-analgetic, woundhealing, anti-hemorrhoid, anti-diabetic, and estrogenic effects. However, most of its pharmacological activities were based on the crude extracts and the bioactive compounds responsible for the bioactivities have not been well identified. A further detailed investigation in phytochemistry to identify the bioactive compounds and to investigate the mechanism action of its bioactivities is required. Moreover, a toxicology study is also needed to develop a standardized formulation of G. pictum preparation and to fulfill the requirements of modern phytomedicine.

10aActivities10aG pictum10aIndonesia10aPharmacological1 aMakkiyah, Feda1 aRahmi, Eldiza, Puji1 aRevina, Rika1 aSusantiningsih, Tiwuk1 aSetyaningsih, Yuni uhttps://phcogj.com/article/1432