01922nas a2200289 4500008004100000245007800041210006900119260001400188300001300202490000700215520108200222653001501304653001801319653002601337653001401363100002201377700002701399700002101426700002001447700002401467700002001491700002601511700002101537700002101558700001701579856003601596 2021 eng d00aIsolation and Structural Characterization of Compounds from Blumea lacera0 aIsolation and Structural Characterization of Compounds from Blum cJuly 2021 a999-10040 v133 a
Background: The medicinal plants consider as a rich resource of ingredients which can be used in drug development and synthesis. Blumea lacera (Burm. f.) DC. is generally used in traditional medicine for the treatment of cough, bronchitis, dysentery, wound healing. The aim of this study is to isolate and identify the compounds from the aerial parts of Blumea lacera. Methods: The aerial parts of B. lacera were dried, powdered and extracted using EtOH, and the concentrated extract was partitioned in succession with n-hexane, CH2Cl2, and EtOAc. From the EtOAc fraction, the compounds were isolated through column chromatography and their chemical structures were elucidated by NMR spectroscopy and confirmed by comparison of their NMR data with literature data. Results: Repeated column chromatography of the EtOAc-soluble fraction from the aerial parts of B. lacera resulted in the isolation of β-sitosterol (1), campesterol (2), artemetin (3) and acid paracatechuic (4).
10aAsteraceae10aBlumea lacera10aColumn chromatography10aFlavonoid1 aPham, Xuan, Phong1 aNhung, Tran, Thi Tuyet1 aTrinh, Hoai, Nam1 aTrung, Do, Minh1 aGiang, Dang, Truong1 aVu, Binh, Duong1 aDiep, Nguyen, Trọng1 aVan Long, Nguyen1 aNguyen, Van, Thu1 aVan Men, Chu uhttps://phcogj.com/article/1624