01938nas a2200217 4500008004100000245011200041210006900153260001500222300001200237490000700249520126100256653002701517653001701544653001301561653001001574653002201584100002501606700002701631700002601658856003601684 2022 eng d00aGC-MS Profiling, Antioxidants and Antimicrobial Activity of Prickly Pear (Opuntiaficus-indica) Pulp Extract0 aGCMS Profiling Antioxidants and Antimicrobial Activity of Prickl cApril 2022 a262-2670 v143 a

The objective of this study was to evaluate phytochemical screening, antioxidants and antimicrobial activity of prickly pear pulp extract. Phytochemical screening was performed on the methanolic extract of the sample followed by gas chromatography mass spectrometry (GC-MS).The antioxidant activity was determined by measuring total phenolic content (TPC), ferric reducing antioxidant power (FRAP) and 2, 2-diphenyl-1-picrylhydrazyl (DPPH). The antibacterial activity was determined using paper disc method against two bacteria namely Staphylococcus aureus and Escherichia coli. Total of 36 compounds belonging to phenolics, anhydrides, aldehydes, fatty acids and hydrocarbons were identified in the extracts. The highest content of total phenol and antioxidant activity (FRAP and DPPH) were found in methanol extract228.50 ± 3.67. mg GAE/100g DW, 118.63 ±3.86 mg TE/100g DW and 92.81% respectively. The maximum zone of inhibition observed was 14.45 ± 0.67 mm against Staphylococcus aureus at methanol extract. It was concluded that fractions solvent plays important roles on the bioactive compound of prickly pear pulp extract and it can be used to control infectious diseases and prevent oxidative damage.

10aAntibacterial activity10aAntioxidants10aFraction10aGC-MS10aPrickly pear pulp1 aAddai, Zuhair, Radhi1 aAbood, Meethaq, Satter1 aHlail, Shrrog, Hammed uhttps://phcogj.com/article/1761