01676nas a2200181 4500008004100000245008700041210006900128260001600197300001200213490000700225520110600232653002001338653003101358653002601389100002001415700002301435856003601458 2022 eng d00aTriterpenoids from Agathis robusta Aerial Parts and Their Hepatopotective Activity0 aTriterpenoids from Agathis robusta Aerial Parts and Their Hepato cAugust 2022 a362-3660 v143 a

Objective: While Agathis robusta contains important phytochemical constituents and has been linked to a variety of biological activities, there is currently insufficient research on the plant's total phytochemical constituents or pharmacological activity. Materials and Procedures: The aerial part of Agathis robusta was extracted with 70% methanol and was screened for new phytochemical components. The structures of the isolated compounds were elucidated by spectroscopic data interpretation. The hepatoprotective activity of the isolated compounds was investigated. Results: Four known triterpenoids and two new compounds were isolated for the first time from the methanolic extract of the aerial parts of A. robusta. Conclusion: For the first time, new triterpenoidal saponins with high hepatoprotective activity have been isolated from the aerial portion of A. robusta. As a result, it is suggested that more emphasis be placed on this plant's biological behavior.

10aAgathis robusta10aHepatoprotective activity.10aTriterpenoid saponins1 aAhmed, Amal, H.1 aMohamed, Shaza, A. uhttps://phcogj.com/article/1843