02012nas a2200241 4500008004100000245009900041210006900140260001600209300001200225490000700237520130700244653003901551653002301590653001701613100001801630700000501648700002001653700002601673700000501699700000501704700002501709856003601734 2022 eng d00aNephrotic Syndrome with Focal Segmental Glomerulosclerosis Histological Feature: A Case Report0 aNephrotic Syndrome with Focal Segmental Glomerulosclerosis Histo cAugust 2022 a459-4610 v143 a

Introduction: Nephrotic syndrome is a clinical syndrome of heavy proteinuria and hypoalbuminemia or hypoproteinemia. Renal biopsy is fundamental to assess not only the type but also the degree of disease activity. The overall prognosis and response to treatment often depend on the severity of histological lesions and their reversibility.1,2 Case Presentation: An eighteen years old man with nephrotic syndrome and planned for a kidney biopsy. This case showed a patient with swollen face (especially on the cheek). On Biopsy results showing the glomerulus proliferation of cells and mesangeal matrix, adhesions in (50%) glomerulus, focal sclerosis in some glomeruli, erythrocyte cells visible in the urinary space and thickening of the basement membrane in some glomeruli, partially atrophic tubules, visible erythrocytes in the tubular lumen. Conclusion: An eighteen years old man with nephrotic syndrome with cushing syndrome and hypokalemia who had a renal biopsy. The histological feature from the renal biopsy was focal segmental glomerulosclerosis. The underlying cause of FSGS is still unclear. Assessing the diagnosis and etiology become important to direct the subsequent clinical approach and therapy

10aFocal segmental glomerulosclerosis10aNephrotic syndrome10aRenal biopsy1 aSamudra, Dian1 a1 aMardiana, Nunuk1 aTjempakasari, Artaria1 a1 a1 aRahaju, Anny, Setijo uhttps://phcogj.com/article/1856