02596nas a2200289 4500008004100000024000700041245009300048210006900141260001500210300001200225490000700237520165900244653001201903653001501915653001901930653002701949653001801976100003901994700003502033700003502068700002602103700003402129700003502163700003802198700003402236856003602270 2023 eng d a1700aEffect of Rosmarinus Officinalis Essential Oil On Anxiety, Depression, And Sleep Quality0 aEffect of Rosmarinus Officinalis Essential Oil On Anxiety Depres cApril 2023 a343-3490 v153 a

Introduction: The objective of this investigation was to evaluate the effect of Rosmarinus officinalis essential oil on anxiety, depression, and sleep quality. Methods: The essential oils were extracted by hydro-distillation using a modified Clevenger-type apparatus and the chemical composition was performed by Gas chromatography with flame ionization detection (GC-FID) and Gas chromatography mass spectrometry (GC–MS). Furthermore, a quasi-experimental study was conducted, where 81 participants were divided into two groups, comprising a waiting list control group and an experimental group treated with essential oils. Anxiety and depression indexes were evaluated using the Zung Self-Rating Anxiety Scale (SAS) and the Zung Self-Rating Depression Scale (SDS), and sleep quality was measured with the Pittsburgh Sleep Quality Inventory (PSQI). Results: Chemical analysis showed that 1,8 cineole (37.6%), α-pinene (19.9%), and linalool (15.8%) were the main components. Anxiety, depression, and sleep quality scores showed a decrease in the post-test study phase compared to the pre-test in the experimental group (p<0.05). A large size effect was found in the case of anxiety (d = 1.491; g= 1.490) with 1-β=0.996, while medium size effects were observed for depression (d = 0.581; g= 0.582) with 1-β=0.585; and sleep quality (d = 0.586; g = 0.588) with 1-β=0.638. Conclusion: Essential oils extracted from Rosmarinus officinalis are more effective in calming anxiety and show moderate changes in depression and sleep quality.

10aAnxiety10aDepression10aEssential oils10aRosmarinus officinalis10aSleep quality1 aAlvarado-García, Paul, Alan Arkin1 aSoto-Vásquez, Marilú, Roxana1 aRosales-Cerquin, Luis, Enrique1 aBenites, Santiago, M.1 aCubas-Romero, Taniht, Lisseth1 aJara-Aguilar, Demetrio, Rafael1 aGavidia-Valencia, José, Gilberto1 aAlfaro-Beltrán, Iris, Melina uhttps://phcogj.com/article/2006