02125nas a2200193 4500008004100000245013500041210006900176260001800245300001400263490000700277520149000284653002001774653002201794653001701816653002201833100001601855700002401871856003601895 2023 eng d00aPhysicochemical and antistaphylococcal evaluation of two herbal ointments from Mikania micrantha Kunth and Tridax procumbens Linn0 aPhysicochemical and antistaphylococcal evaluation of two herbal  cDecember 2023 a1042-10460 v153 a

Objectves: This present work was carried out to formulate and evaluate herbal ointments using Mikania micrantha and Tridax procumbens. Materials and Methods: The extracts were prepared using maceration technique. A simple ointment base was prepared using white soft paraffin and liquid paraffin. The extracts were incorporated into the ointment base following levigation method. The amount of extract to be incorporated into the ointment base was determined according to their minimum inhibitory concentration (MIC) against Staphylococcus aureus MTCC 87. The formulated ointments were evaluated for several physicochemical characteristics like colour, odour, homogeneity, washability, spredability, irritation potential etc. Antistaphylococcal assay was conducted using well diffusion method. Ointment base containing white soft paraffin and liquid paraffin was used as negative control and Supragent containing Gentamicin sulphate was used as a positive control. Results: The formulated ointments showed satisfactory results for tested physicochemical parameters. Both ointments showed moderate antistaphylococcal activity with reference to the activity showed by Supragent. Conclusion: The results of this study indicate that the formulated ointments can be incorporated into India’s medicine system for treating Staphylococcus aureus induced skin ailments in future.

10aHerbal ointment10aMikania micrantha10aSkin disease10aTridax procumbens1 aBera, Arnab1 aBanerjee, Nilanjana uhttps://phcogj.com/article/2159