03116nas a2200409   4500008004100000245014400041210006900185260001700254300001400271490000700285520171600292653002102008653002202029653001902051100003102070700003302101700003302134700003202167700002902199700003002228700003102258700001902289700002302308700002302331700002902354700003002383700003202413700002702445700003202472700003002504700003102534700002602565700002802591700002702619700002402646856003602670       2024                        eng d00aInfluence of Chamomile Leaves extract in Different Doses on Renal Functions and Diabetic indices in Streptozotocin – Induced Diabetic Rat0 aInfluence of Chamomile Leaves extract in Different Doses on Rena  cOctober 2024  a1029-10350 v163 a<p class="rtejustify"><strong>Background:</strong> The prevalence of diabetes among Egyptians is rising. Therefore, there is always a demand for innovative natural medicines. Medicinal plants have long been a significant source in search of novel, effective alternatives for human therapy. Chamomile is one of the most widely used medicinal plants, which may help hyperglycemic patients by lowering blood sugar levels. Objectives: To determine how chamomile extract affects the kidneys when albino male rats with chronic diabetes are induced by streptozotocin (STZ). <strong>Methods:</strong> The study was conducted in the Al-Azhar Faculty of Medicine (Assiut) pharmacology department animal laboratory. For this investigation, a local strain of fifty adult male albino rats was used as the animal model and weighed 120 to 150 g. In this study, rats were divided into five groups, body weight, and systolic blood pressure was measured, and blood samples were collected for measuring blood glucose and insulin level, HbA1c, Na, K, and renal function tests, and histopathological examination was done. <strong>Results:</strong> After the study, mean glucose levels, HbA1c, urea, creatinine, K, and systolic blood pressure were significantly decreased in group IV &amp; group V compared to group III. In contrast, body weight serum insulin level and Na increased dramatically in group IV &amp; group V compared to group III.<strong> Conclusion:</strong> The serum levels of urea and creatinine in diabetic patients may be positively affected by chamomile. Additionally, short-term chamomile uses benefits diabetic individuals by decreasing loss of body weight, lowering HbA1c, and increasing insulin levels.</p>
10aChamomile leaves10aDiabetes mellitus10aStreptozotocin1 aAhmed, Mohamed, Zaeim Hafe1 aElfiky, Muhammad, Abdelbaeth1 aMohamed, Elsayed, Elagamy El1 aThabet, Ramadan, Hassan Ibr1 aAllah, Ahmed, Mohamed Ga1 aElsisi, Ahmed, Abdrabo El1 aMohamed, Ahmed, Abdel Nass1 aShikhon, Tarek1 aAbo-akrab, Mostafa1 aA.M.Mahmoud, Sayed1 aDoma, Mohamed, AbdelAziz1 aKhattab, Wael, Ahmed Mahm1 aElhamaky, Khaled, Saleh Ali1 aSalamoni, Mohamed, El-1 aAbdelraheem, Fatma, Mahmoud1 aAzab, Mahmoud, Ahmad Moha1 aAzab6, Mahmoud, Ahmad Moha1 aEL-Refaey, Mohamed, E1 aEl-Rhman, Ahmed, A. Abd1 aGhany, Ahmed, F. Abdel1 aHegazy, Ghada, Adel  uhttps://phcogj.com/article/2378