01928nas a2200217 4500008004100000245015400041210006900195260001400264300001200278490000600290520113200296653002901428653001701457653002701474653005401501653001701555100002801572700002601600700003401626856005001660 2017 eng d00aActive Constituents of Pomegranates (Punica granatum) as Potential Candidates in the Management of Health through Modulation of Biological Activities0 aActive Constituents of Pomegranates Punica granatum as Potential cJuly 2017 a689-6950 v93 a

Pomegranates fruits have innumerable health benefits and its implication in diseases cure have been widely recognized since ancient time. Moreover, pomegranate fruits, seeds and peels are intensively used in traditional medicine as a natural therapy. It contains numerous valuable ingredients such as flavonoids, ellagitannin, punicalagin, ellagic acid, vitamins and minerals. The principal constituents including punicalagins and ellagitannin are responsible for immeasurable health benefits due to its strong antioxidant activity. Additionally, constituents of pomegranate show health promoting effect through the modulation of physiological and biochemical pathways. Recent evidences suggested that pomegranates fruits, peels and seeds illustrate therapeutics implications in health management via inhibition of free radical effect and modulation of enzymes activity linked with diseases development and progression. In this review, we summarize the therapeutic role of pomegranate fruits, seeds and peels in the health managements based on in vitro and in vivo studies.

10aAnti-inflammatory Effect10aAnti-oxidant10aHeptoprotective Effect10aNeuroprotective Effect and Anti-microbial Effects10aPomegranates1 aRahmani, Arshad, Husain1 aAlsahli, Mohamed, Ali1 aAlmatroodi, Saleh, Abdulrahma u/files/pj-9-5/10.5530pj.2017.5.109/index.html