02439nas a2200217   4500008004100000245013900041210006900180260001900249300001200268490000600280520171700286653002002003653001902023653001502042653001002057653001902067100004102086700003402127700002502161856003502186       2017                        eng d00aPhytochemical Evaluation and Chromatographic Fingerprint Analysis on Flavonoids Compounds in Leucas aspera (Willd.) Link Leaf by HPTLC0 aPhytochemical Evaluation and Chromatographic Fingerprint Analysi  cSeptember 2017  a942-9460 v93 a<p style="text-align: justify;"><strong>Introduction:</strong> <em>Leucas aspera</em> is one of the important medicinal plants in Indian medical system and it belongs to Lamiaceae family. <em>Leucas aspera</em> (Willd) Link (<em>L. aspera</em>) belongs to Leucas genus, widely distributed throughout India. <em>L. aspera</em> has many vernacular names and is commonly known as Thumbai. Flavonoid is a phenolic compound which is widely distributed in the plants and responsible for many biological activities. Preliminary phytochemical analysis gives a broad idea to the researchers for their further research. <strong>Methods:</strong> In this present study, we did a preliminary phytochemical screening, quantitative estimation of total flavonoids and fingerprinting profile of flavonoids compounds using five different solvent extracts obtained from leaves of <em>L. aspera.</em> <strong>Results:</strong> Preliminary phytochemical screening confirmed the presence of flavonoid compounds in <em>L. aspera</em>. Higher concentration of total flavonoid compounds was noted in ethanol extract compared to petroleum ether, chloroform, isopropyl alcohol and ethyl acetate extracts. A densitometric high performance thin layer chromatography (HPTLC) study showed more number of flavonoid compounds are present in ethanol extract compared to other solvents. <strong>Conclusions:</strong> Results of this study revealed, <em>L. aspera</em> leaf is a rich source of flavonoid content and it can be used to alleviate many chronic illness and various diseases. This study results warrants for further isolation, identification and characterization of active principle which is responsible for the biological activity.</p>10aChromatographic10aFingerprinting10aFlavonoids10aHPTLC10aLeucas aspera.1 aAnnapandian, Vellaichamy, Muthupandi1 aSundaram, Rajagopal, Shanmuga1 aGomathi, Swaminathan  uhttp://fulltxt.org/article/200