02948nas a2200253 4500008004100000245011600041210006900157260001800226300001000244490000700254520215600261653002702417653002102444653002202465653002602487653002102513653002302534100002002557700002202577700002102599700002002620700001902640856003502659 2018 eng d00aComposition and Antibacterial Activity of Hydro-Alcohol and Aqueous Extracts Obtained from the Lamiaceae Family0 aComposition and Antibacterial Activity of HydroAlcohol and Aqueo cDecember 2017 a81-910 v103 a

Context: Plant from the Lamiaceae family are considered as dietary spices and medicinal herbs traditionally used in medicine for the treatment of several pathologies. Objective: Evaluation of the in vitro antibacterial activity of ethanol and aqueous extracts of nine Moroccan plants from the Lamiaceae family against six bacterial strains regularly implicated in toxiinfection. Method: The antibacterial activities of hot (HAE), cold (CAE) aqueous extracts and ethanolic extracts (EE) were evaluated using agar-well diffusion method, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and IC50 against six foodborne bacteria (Bacillus cereus, Listeria monocytogenes, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Salmonella enterica). Total phenolic and flavonoid contents were assessed as well. Results: In the present study, the ethanol extracts were rich in polyphenols, with middling values of flavonoids, and relatively poor in condensed tannins. The presence of saponins, essential oils, irroides, alkaloids, anthocyanins, and aldehydes was recorded. The effect of the extracts was directly bactericidal for B. cereus and L. monocytogenes; for the other strains, the MBC value was twice higher than that of MIC. However, the ethanol extract (EE) of O. majorana and T. satureioides showed the highest antibacterial activity. With the principal component analysis, it was demonstrated that the nine Lamiaceae family plants possess a powerful antibacterial effect, correlated with their phenolic content. Statistical analysis: Analysis of variance was performed by uni-varied ANOVA in the software SPSS 22 Fr. Conclusion: The active compounds were thermostable and soluble in ethanol and water. The antimicrobial activities of the plants extracts investigated may contribute to understand their involvement in traditional medicine against many microbial infections.

10aAntibacterial activity10aAqueous Extract.10aFlavonoic Content10aHydro-Alcohol Extract10aLamiaceae Family10aPhenolic compounds1 aBtissam, Ramdan1 aFatima, El, Malki1 aKamal, Eddarraji1 aHassane, Greche1 aMohamed, NHIRI uhttp://fulltxt.org/article/402