01683nas a2200193 4500008004100000245011800041210006900159260001700228300001200245490000700257520105000264653001601314653001601330653002901346653003001375653003101405100001801436856003501454 2018 eng d00aChromosomal Disturbances during Mitotic Activity of Root Tip Cells in Allium by Certain Commonly Used Antibiotics0 aChromosomal Disturbances during Mitotic Activity of Root Tip Cel cJanuary 2018 a355-3650 v103 a

Introduction: The certain commonly used antibiotics (cefixime, metronidazole, ciprofloxacin, cefpodoxime and cetirizine) purchased from the chemist shop in Mokokchung town, Nagaland and effects on mitotic activity of root tip meristematic cells of Allium Cepa were observed. Methods: The different concentrations were prepared by retaining the original effective concentrations (400, 400, 500, 200 and 10 mg) of the antibiotics and treated the root tips of Allium at different times (6, 12 and 24 h) to record the effects or abnormalities. Results: All the concentrations (ppm) and time (h) were effective to induce the chromosomal disturbances during the mitotic activity of root tip cells in Allium. Conclusion: The mean value (±S.E.) recorded for mitotic cells, mitotic stages, physiological and clastogenic abnormalities and showed a mixed response which could not predict dose response curve in actual.

10aAllium cepa10aAntibiotics10aChromosomal disturbances10aClastogenic abnormalities10aPhysiological disturbances1 aKumar, Sanjay uhttp://fulltxt.org/article/490