02494nas a2200277 4500008004100000245013400041210006900175260001600244300001400260490000700274520160700281653001801888653002401906653002901930653002401959653002301983100001802006700002402024700002602048700002002074700001802094700002502112700002102137700002302158856003502181 2018 eng d00aLarvicidal and Pupicidal activity of Clerodendrum philippinum Schauer Leaf Extracts against Anopheles stephensi and Aedes aegypti0 aLarvicidal and Pupicidal activity of Clerodendrum philippinum Sc cAugust 2018 a1137-11420 v103 a

Objective: The purpose of this study is to investigate the larvicidal and pupicidal activity of Clerodendrum philippinum leaf extracts against disease causing vectors Anopheles stephensi and Aedes aegypti. Methods: Five different concentrations (200, 300, 400, 500 and 600 ppm) of leaves were prepared by using aqueous (distilled water), ethanol, methanol, n-hexane, chloroform and tested for both the activity. The LC50 and LC90 values of leaf extracts were determined with the help of probit analysis. Results: Among the different extracts of leaf screened, the ethanol extract of C. philippinum was recorded the highest larvicidal and pupicidal activity of 100 ± 1.9 % (1st instar) and 58 ± 0.8 % at 600 ppm concentration for controlling An. stephensi, respectively. Similarly for Ae. aegypti, 97 ± 1.2 (1st instar) and 51 ± 0.5 (pupa) percentage of inhibition were achieved for the same solvent extracts of the leaf which were maximum than others. Moreover, the values of LC50 and LC90 clearly indicate that the activity of both larvicidal and pupicidal are not only solvent extracts dependant but also depend on their concentration. Conclusion: The obtained data highlight the potential role of ethanolic extracts of C. philippinum for controlling An. stephensi and Ae. aegypti mosquitoes at their larval and/ pupal stages of development.

10aAedes aegypti10aAnopheles stephensi10aClerodendrum philippinum10aLarvicidal activity10aPupicidal activity1 aDhal, Pranati1 aRout, Jyoti, Ranjan1 aDash, Preeti, Krishna1 aPanda, Sagorika1 aPati, Pallabi1 aRath, Chandi, Charan1 aPradhan, Chinmay1 aSahoo, Santi, Lata uhttps://phcogj.com/article/731