TY - JOUR T1 - Evaluation of Antioxidant and Anticancer Activity of Myristica fragrans Houtt. Bark JF - Pharmacognosy Journal Y1 - 2021 A1 - Binawati Ginting A1 - Mustanir A1 - Nurdin A1 - Maulidna A1 - Murniana A1 - Safrina KW - Anticancer KW - Antioxidant KW - Bark KW - n-hexane extract KW - Nutmeg (Myristica fragrans Houtt) AB -

This study aims to evaluate the antioxidant and anticancer activity of secondary metabolite compounds from Myristica fragrans Houtt. (nutmeg) bark using n-hexane extract based on DPPH radical scavenging and microculture tetrazolium salt (MTT) assay. The chemical structural analysis using NMR, FTIR, and LC-MS spectroscopy confirmed and identified the structure of isolated compound namely (2E)-5(2z.4E)-hexa-2,4,-dio-zyl)-2propylcyclohexanol (C18H30O4) for the first time which is corresponding for the excellent antioxidant and anticancer activity against MCF-7 cell lines with the IC50 value of 99.76 and 10.75 ppm, respectively.

VL - 13 IS - 3 ER -