TY - JOUR T1 - Potential of Ethanolic Extract from Ripe Musa balbisiana Colla Fruit Using Ultrasound-Assisted Extraction as An Antioxidant and Anti-Gout JF - Pharmacognosy Journal Y1 - 2021 A1 - Candra Irawan A1 - Andita Utami A1 - Erna Styani A1 - Imalia Dwi Putri A1 - Ratna Komala Putri A1 - Avisani Dewanta A1 - Annisa Ramadhanti KW - Anti-gout KW - Antioxidant KW - Musa balbisiana Colla KW - Phenolic content KW - UAE AB -

Plant extracts or their secondary metabolites have functioned as antioxidants in phytotherapy drugs which function as protection against various diseases related to oxidative stress and free radicals. Free radicals play an important role in the initiation and development of various diseases, one of which is uric acid. Hhis study aims to obtain ethanolic extract from the ripe fruit of Musa balbisiana Colla using the UAE method and obtain information about secondary metabolites and their bioactivity as antioxidants and anti-gout. The results showed that antioxidant activity test using the DPPH and FRAP methods gave IC50 values of 150.24 ± 0.0348 mg/L and 227.80 ± 0.0986 mg / L, respectively. The total phenolic content value of 625.64 ± 0.36 mg GAE/g ethanolic extract is thought to have a role in high antioxidant activity. In addition, ethanol extract with a concentration of 50 mg / L has activity in reducing uric acid levels by around 9%. It can be concluded that the ethanolic extract produced by UAE has potential as a source of anti-oxidants and anti-gout.

VL - 13 IS - 6 ER -