TY - JOUR
T1 - In-vivo Hepatoprotective Activity of Methanolic Extracts of Sphaeranthus amaranthoides and Oldenlandia umbellate
JF - Pharmacognosy Journal
Y1 - 2017
A1 - Somnath De
A1 - Ramalingam Suresh
A1 - Akula Murali Sri Sudhakar Babu
A1 - Siddabathuni Aneela
KW - ALP
KW - CCl4
KW - Hepatoprotective activity
KW - Oldenlandia umbellata
KW - SGOT
KW - SGPT
KW - Sphaeranthus amaranthoides
KW - TB.
AB -
Objective: The present study was carried out to evaluate the in vitro hepatoprotective activity of unexploited plants, Sphaeranthus amaranthoides and Oldenlandia umbellate on CCl4 induced liver injury, which are indigenous to South India. Methods: in the present study the methanolic extracts from Sphaeranthus amaranthoides and Oldenlandia umbellata were studied against the carbon tetrachloride hepatotoxicity. Results: significant hepatoprotective effect was obtained against carbon tetrachloride induced liver damage as judged from serum marker enzyme activities (SGOT, SGPT, ALT, and TB) and a normal architecture of liver compare to toxic control. Conclusion: the result revealed that methanolic extracts of Sphaeranthus amaranthoides and Oldenlandia umbellata could be useful in preventing CCl4 induced liver injury.
VL - 9
IS - 1
ER -