TY - JOUR T1 - Larvicidal and Pupicidal activity of Clerodendrum philippinum Schauer Leaf Extracts against Anopheles stephensi and Aedes aegypti JF - Pharmacognosy Journal Y1 - 2018 A1 - Pranati Dhal A1 - Jyoti Ranjan Rout A1 - Preeti Krishna Dash A1 - Sagorika Panda A1 - Pallabi Pati A1 - Chandi Charan Rath A1 - Chinmay Pradhan A1 - Santi Lata Sahoo KW - Aedes aegypti KW - Anopheles stephensi KW - Clerodendrum philippinum KW - Larvicidal activity KW - Pupicidal activity AB -

Objective: The purpose of this study is to investigate the larvicidal and pupicidal activity of Clerodendrum philippinum leaf extracts against disease causing vectors Anopheles stephensi and Aedes aegypti. Methods: Five different concentrations (200, 300, 400, 500 and 600 ppm) of leaves were prepared by using aqueous (distilled water), ethanol, methanol, n-hexane, chloroform and tested for both the activity. The LC50 and LC90 values of leaf extracts were determined with the help of probit analysis. Results: Among the different extracts of leaf screened, the ethanol extract of C. philippinum was recorded the highest larvicidal and pupicidal activity of 100 ± 1.9 % (1st instar) and 58 ± 0.8 % at 600 ppm concentration for controlling An. stephensi, respectively. Similarly for Ae. aegypti, 97 ± 1.2 (1st instar) and 51 ± 0.5 (pupa) percentage of inhibition were achieved for the same solvent extracts of the leaf which were maximum than others. Moreover, the values of LC50 and LC90 clearly indicate that the activity of both larvicidal and pupicidal are not only solvent extracts dependant but also depend on their concentration. Conclusion: The obtained data highlight the potential role of ethanolic extracts of C. philippinum for controlling An. stephensi and Ae. aegypti mosquitoes at their larval and/ pupal stages of development.

VL - 10 IS - 6 ER -