<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Girish H V</style></author><author><style face="normal" font="default" size="100%">Vinod A B</style></author><author><style face="normal" font="default" size="100%">Dhananjaya B L</style></author><author><style face="normal" font="default" size="100%">Satish Kumar D</style></author><author><style face="normal" font="default" size="100%">Senthil Duraisamy</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Anticancer Potential of Pavonia odorata extract on Human Breast (MD-MB-231), Prostate (PC-3) and Lung (Calu-6) Cancer cell lines</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Alternative medicine</style></keyword><keyword><style  face="normal" font="default" size="100%">Anti-cancer</style></keyword><keyword><style  face="normal" font="default" size="100%">Drugs</style></keyword><keyword><style  face="normal" font="default" size="100%">Indian Medicinal plants</style></keyword><keyword><style  face="normal" font="default" size="100%">Inhibition.</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">09/2015</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">28-30</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;margin-left: -9pt; text-align: justify;&quot;&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; A huge reservoir of bioactive compounds exists in many species of plants, only a small percentage of which have been examined and continued to be an important source of anticancer agents. Worldwide effects are ongoing to identify new anticancer compounds from plants. With the current decline in the number of new molecular entities from the pharmaceutical industry, novel anticancer agents are being sought from traditional medicines. &lt;strong&gt;Objective:&lt;/strong&gt; In the present study we investigated the efficacy of methanol extracts of &lt;em&gt;Pavonia odorata, &lt;/em&gt;for its clonogenic inhibition on Human Breast cancer (MD-MB-231), Prostate cancer (PC-3) and Lung cancer (Calu-6) cell lines. &lt;strong&gt;Materials and&lt;/strong&gt; &lt;strong&gt;Methods:&lt;/strong&gt; The cytotoxic effect was evaluated by MTT assay. &lt;strong&gt;Results:&lt;/strong&gt; The methanol extract of &lt;em&gt;P. odorata &lt;/em&gt;showed significant cytotoxicity against MD-MB-231 and Calu-6, when compared to PC-3cells&lt;em&gt;. &lt;/em&gt;&lt;strong&gt;Conclusion:&lt;/strong&gt; The methanol extracts of &lt;em&gt;P. odorata, &lt;/em&gt;showed effective cytotoxic activities in a dose dependent manner. Future work will be interesting to know the chemical composition and also better understanding the mechanism of action will help in developing it as drug for therapeutic application.&lt;/p&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">28</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Girish H V&lt;sup&gt;1&lt;/sup&gt;, Vinod A B&lt;sup&gt;1&lt;/sup&gt;, Dhananjaya B L&lt;sup&gt;2&lt;/sup&gt;, Satish Kumar D&lt;sup&gt;1&lt;/sup&gt; and Senthil Duraisamy&lt;sup&gt;1&lt;/sup&gt; &lt;/strong&gt;&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Phytochemistry, G7 Synergon Private Limited, Tatanagar, Sahakarnagar Post, Bangalore, India.&lt;/p&gt;

&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Toxinology/Toxicology and Drug Discovery Unit, Centre for Emerging Technologies (CET), Jain University, Kanakpura Taluk, Ramanagara-562112, India.&lt;/p&gt;</style></auth-address></record></records></xml>