<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Buavaroon Srichaikul</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Bioactivity and Extraction Method with Ultrasonication of Nelumbo nucifera Linn. Anti Aging Drinks</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Acute toxicity</style></keyword><keyword><style  face="normal" font="default" size="100%">Flavonoids</style></keyword><keyword><style  face="normal" font="default" size="100%">Flower extract drink</style></keyword><keyword><style  face="normal" font="default" size="100%">HPLC</style></keyword><keyword><style  face="normal" font="default" size="100%">Nelumbo nucifera Linn.</style></keyword><keyword><style  face="normal" font="default" size="100%">Phenolic content</style></keyword><keyword><style  face="normal" font="default" size="100%">Ultra sonication Extraction</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2020</style></year><pub-dates><date><style  face="normal" font="default" size="100%">August 2020</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">12</style></volume><pages><style face="normal" font="default" size="100%">1097-1103</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction:&lt;em&gt; &lt;/em&gt;&lt;/strong&gt;&lt;em&gt;Nelumbo nucifera&lt;/em&gt; Linn. Flowers health drinks currently are one of the popular demand globally in Thailand and all over the world. There are plenty of substandard or over claimed of antioxidant content labeled at health drink bottles. The consumers do not obtain enough health benefits anti-oxidant contents which are destroyed by heat during their production process. &lt;strong&gt;Methods: &lt;/strong&gt;This study aimed to evaluate the optimization of extraction including water, 40 % and 50% ethyl alcohol using maceration and ultra-sonication method to obtain the highest antioxidant activity compared with DPPH, FRAP and ABTS methods were investigated including total phenolic and flavonoid contents by HPLC in different period of time. The analysis of acute toxicity in white wistar rats by oral administrating of &lt;em&gt;Nelumbo nucifera&lt;/em&gt; Linn. flowers extract was testing for after 24 h and 14 d. &lt;strong&gt;Results:&lt;/strong&gt; It was found that &lt;em&gt;Nelumbo nucifera&lt;/em&gt; Linn. flower extract drink consisted of high contents of gallic acid, catechin and rutin by HPLC method.&lt;em&gt; Nelumbo nucifera&lt;/em&gt; Linn flowers Highest Total Phenolic compound in Nelumbo nucifera Linn. flower extracts with sonicating with 50% ethanol was 0.954639 ± 0.109672. Highest Total flavonoids in &lt;em&gt;Nelumbo nucifera&lt;/em&gt; Linn. flower extracts macerating in 50 % ethanol at day 5th was 1.100275 ± 0.777271.and the sonication with 40% ethanol was 0.394283+/- 0.51175. &lt;strong&gt;Conclusions:&lt;/strong&gt; The result of acute toxicity analysis showed no toxicity.&lt;em&gt; Nelumbo nucifera &lt;/em&gt;Linn. flower extract drinks which are safe as a health drink for consumers. The further market analysis with sensory test should be essential for further research.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1097</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Buavaroon Srichaikul* &lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;Faculty of Public Health, Mahasarakham University, Mahasarakham 44150, THAILAND.&lt;/p&gt;
</style></auth-address></record></records></xml>