<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Phimkun Aiyarakanchanakun</style></author><author><style face="normal" font="default" size="100%">Chanida Palanuvej</style></author><author><style face="normal" font="default" size="100%">Nijsiri Ruangrungsi</style></author><author><style face="normal" font="default" size="100%">Anuchit Phanumartwiwath</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Pharmacognostic Specifications, RP-HPLC Analysis of Chlorogenic Acid Content and Antioxidant Activity of Morus alba Linn. Leaves in Thailand</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">antioxidant activity</style></keyword><keyword><style  face="normal" font="default" size="100%">Chlorogenic acid</style></keyword><keyword><style  face="normal" font="default" size="100%">Morus alba</style></keyword><keyword><style  face="normal" font="default" size="100%">Pharmacognostic specification</style></keyword><keyword><style  face="normal" font="default" size="100%">Quality control</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2021</style></year><pub-dates><date><style  face="normal" font="default" size="100%">September 2021</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">13</style></volume><pages><style face="normal" font="default" size="100%">1186-1194</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background:&lt;/strong&gt; Morus alba Linn. leaves have been widely used as herbal medicine with therapeutics and contain chlorogenic acid as a bioactive phenolic compound. &lt;strong&gt;Objective:&lt;/strong&gt; The present study aimed to conduct the pharmacognostic specifications of M. alba leaves and the method validation for quantification of chlorogenic acid content. &lt;strong&gt;Materials and Methods: &lt;/strong&gt;Macroscopic- and microscopic characteristics, physicochemical parameters combined with quantification of chlorogenic acid in &lt;em&gt;M. alba &lt;/em&gt;leaves collected from 15 sources throughout Thailand and their antioxidant activity were reported in this study. &lt;strong&gt;Results: &lt;/strong&gt;The physicochemical parameters of&lt;em&gt; M. alba&lt;/em&gt; leaves were determined by indicating water content (7.97 ± 0.35%), loss on drying (4.55 ± 0.21%), total ash (14.38 ± 0.25%), acid-insoluble ash (6.21 ± 0.37%), water-extractive value (16.14 ± 0.50%) and ethanol-extractive value (8.61 ± 0.39%). In addition, the chlorogenic acid contents in &lt;em&gt;M. alba&lt;/em&gt; leaves were found to be 0.4159 ± 0.1958 g/100g dry weight. The ethanolic leaf extracts exhibited their antioxidant activity with half-maximal inhibitory concentration (IC&lt;sub&gt;50&lt;/sub&gt;) values (326.09–467.55 μg/mL). &lt;strong&gt;Conclusion: &lt;/strong&gt;This study showed the establishment of pharmacognostic study of&lt;em&gt; M. alba&lt;/em&gt; leaves and validation of the reversed-phase high-performance liquid chromatography (RPHPLC) quantitative analysis of their chlorogenic acid contents, which are applicable to be a reference for quality control and standardization of &lt;em&gt;M. alba&lt;/em&gt; leaves.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1186</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Phimkun Aiyarakanchanakun&lt;sup&gt;1&lt;/sup&gt;, Chanida Palanuvej&lt;sup&gt;1&lt;/sup&gt;, Nijsiri Ruangrungsi&lt;sup&gt;1,2&lt;/sup&gt;, Anuchit Phanumartwiwath&lt;sup&gt;1,&lt;/sup&gt;*&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;College of Public Health Sciences, Chulalongkorn University, Bangkok, THAILAND.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy, College of Pharmacy, Rangsit University, Pathum Thani, THAILAND.&lt;/p&gt;
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