<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Iram Nazish</style></author><author><style face="normal" font="default" size="100%">S H Ansari</style></author><author><style face="normal" font="default" size="100%">Poonam Arora</style></author><author><style face="normal" font="default" size="100%">Adil Ahmad</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Antiobesity activity of Zingiber officinale</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">High-fat diet</style></keyword><keyword><style  face="normal" font="default" size="100%">Insulin.</style></keyword><keyword><style  face="normal" font="default" size="100%">Leptin</style></keyword><keyword><style  face="normal" font="default" size="100%">Rat</style></keyword><keyword><style  face="normal" font="default" size="100%">Zingiber officinale</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2016</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Oct 2016</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">8</style></volume><pages><style face="normal" font="default" size="100%">440-446</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;&lt;strong&gt;Context: &lt;/strong&gt;&lt;em&gt;Zingiber officinale&lt;/em&gt; Roscoe (Zingiberaceae) rhizome, known commonly as ginger is extensively used in Indian traditional system of medicine for treatment of various disorders. The ethanolic &lt;em&gt;Z. officinale&lt;/em&gt; extract is reported to have various activity such as antidiabetic, antihyperlipidemic and antioxidant activity in experimental animals. &lt;strong&gt;Objective:&lt;/strong&gt; To evaluate anti-obesity effect of aqueous &lt;em&gt;Z. officinale&lt;/em&gt; extract in murine model of high fat diet (HFD)- induced obesity. Materials and Methods: Male Wistar rats fed with HFD (20 g/day/rat, p.o) for a period of 42 days were used to induce obesity. Aqueous&lt;em&gt; Z. officinale&lt;/em&gt; extract (20 mg/kg b.w.) administered orally to HFD fed rats from day 8 to 50 days for a period of 42 days. Body weight gain, serum lipids, insulin and leptin parameters were measured. &lt;strong&gt;Results:&lt;/strong&gt; Oral feeding of the aqueous&lt;em&gt; Z. officinale&lt;/em&gt; extract (20 mg/kg) to HFD-induced obese rats for a period of 42 days resulted in significant reduction in body weight gain, insulin, leptin, lipids as compared to rats fed HFD alone. Further, the extract also showed significant increase in high density lipoprotein (HDL-C) levels.&lt;strong&gt; Discussion and Conclusion:&lt;/strong&gt; These results show that aqueous&lt;em&gt; Z. officinale&lt;/em&gt; extract possess significant anti-obesity potential.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Original Article</style></work-type><section><style face="normal" font="default" size="100%">440</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Iram Nazish&lt;sup&gt;*1&lt;/sup&gt;, S H Ansari&lt;sup&gt;2&lt;/sup&gt;, Poonam Arora&lt;sup&gt;2&lt;/sup&gt;, Adil Ahmad&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacology, HK College of Pharmacy, Oshiwara, Mumbai, INDIA.&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Hamdard University, Hamdard Nagar, New Delhi, INDIA.&lt;/p&gt;
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