<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Maslichah Mafruchati</style></author><author><style face="normal" font="default" size="100%">Jonathan Makuwia</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Analysis of Royal Jelly Apis Cerana as Therapeutic Candidate in Cbavd Based on Bioinformatics Studies</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Apis Cerana</style></keyword><keyword><style  face="normal" font="default" size="100%">Bioinformatics</style></keyword><keyword><style  face="normal" font="default" size="100%">CBAVD</style></keyword><keyword><style  face="normal" font="default" size="100%">Public health.</style></keyword><keyword><style  face="normal" font="default" size="100%">Therapeutic Candidates</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2023</style></year><pub-dates><date><style  face="normal" font="default" size="100%">March 2023</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">15</style></volume><pages><style face="normal" font="default" size="100%">175-182</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;&lt;em&gt;Apis cerana&lt;/em&gt; honey bee is a honey bee native to Asia that spreads from Afghanistan, China, and Japan to Indonesia. The productivity of &lt;em&gt;Apis cerana &lt;/em&gt;honey bees can produce as much as 2-5 kg of honey per colony in a year. Royal jelly is the queen's nourishment, and it is produced by larvae, adult bees, young worker bees, and male bee larvae. CBAVD contributes to 1–2% of the 20–25% of males with subfertility.&lt;strong&gt; Aim:&lt;/strong&gt; The objective of this study was to evaluate Royal Jelly &lt;em&gt;Apis Cerana &lt;/em&gt;as a potential therapeutic candidate for CBAVD using a bioinformatics approach.&lt;strong&gt; Method:&lt;/strong&gt; This research method consisted of converting nucleotides into amino acids, analyzing the three-dimensional structure of&lt;em&gt; Apis Cerana &lt;/em&gt;Royal Jelly Protein, Ramachandran Plot Analysis, Analysis of Epitope and Allergen Proteins, and Analysis of Proteins that were antigens and toxins. &lt;strong&gt;Results: &lt;/strong&gt;The research results were conducted on six three-dimensional &lt;em&gt;Apis Cerana &lt;/em&gt;Royal Jelly bee protein structures and had very good validity based on the Ramachandran plot, GQME value, and QmeanDisCo value. In addition, this study also obtained the results of proteins that are epitope, antigenic, non-allergenic, and non-toxic. &lt;strong&gt;Conclusion: &lt;/strong&gt;The findings of this study can be used as a basis for therapy against CBAVD.&lt;/p&gt;
&lt;quillbot-extension-portal&gt;&lt;/quillbot-extension-portal&gt;</style></abstract><issue><style face="normal" font="default" size="100%">1</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">175</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p&gt;&lt;strong&gt;Maslichah Mafruchati&lt;sup&gt;1,*&lt;/sup&gt;, Jonathan Makuwia&lt;sup&gt;2&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Veterinary Anatomy, Faculty of Veterinary Medicine (60115), Universitas Airlangga, Mulyorejo, C Campus, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Malawi University of Science and Technology 5196 Limbe, MALAWI&lt;/p&gt;
&lt;quillbot-extension-portal&gt;&lt;/quillbot-extension-portal&gt;</style></auth-address></record></records></xml>