<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Henu Hadiyantama</style></author><author><style face="normal" font="default" size="100%">Lukisiari Agustini</style></author><author><style face="normal" font="default" size="100%">Sutjipto</style></author><author><style face="normal" font="default" size="100%">Evelyn Komaratih</style></author><author><style face="normal" font="default" size="100%">Ismi Zuhria</style></author><author><style face="normal" font="default" size="100%">Pudji Lestari</style></author><author><style face="normal" font="default" size="100%">Ridholia</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">The Role of α-SMA, Type 1 Collagen, and Myofibroblasts in Cicatrizing Conjunctivitis by Alkali Chemical Trauma</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Cicatrizing conjunctivitis</style></keyword><keyword><style  face="normal" font="default" size="100%">Myofibroblasts</style></keyword><keyword><style  face="normal" font="default" size="100%">Type 1 collagen</style></keyword><keyword><style  face="normal" font="default" size="100%">α -SMA</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">May 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">591-596</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Chemical trauma to the eye is a serious condition in the field of ophthalmology and a leading factor contributing to global blindness. Cicatrizing conjunctivitis (CC) is a term used to describe conditions marked by inflammation and the formation of scars on the conjunctiva. CC can have various causes, with one of them being chemical injury to the eye. The development of CC involves the participation of several cytokines and cells, such as α-SMA, Type 1 collagen, and Myofibroblasts. Myofibroblasts have the ability to contract through the utilization of diverse cytoskeletal proteins, which are commonly present in smooth muscle cells, including α-SMA. Actin filaments contribute to mechanically supporting cells, defining cell morphology, and facilitating cell mobility. Actin, in conjunction with myosin, participates in the muscle contraction process within muscle cells. Subsequently, type 1 collagen contributes to the healing of conjunctival wounds by providing a tensile force that aids in the closure of such wounds. As a significant constituent of the extracellular matrix, type 1 collagen plays a crucial role in maintaining the integrity of tissues.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">3</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">591</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Henu Hadiyantama&lt;sup&gt;1&lt;/sup&gt;, Lukisiari Agustini&lt;sup&gt;1*&lt;/sup&gt;, Sutjipto&lt;sup&gt;1&lt;/sup&gt;, Evelyn Komaratih&lt;sup&gt;1&lt;/sup&gt;, Ismi Zuhria&lt;sup&gt;1&lt;/sup&gt;, Pudji Lestari&lt;sup&gt;2&lt;/sup&gt;, Ridholia&lt;sup&gt;3&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Ophthalmology, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Academic Hospital, Surabaya, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Public Health, Faculty of Medicine, Universitas Airlangga, Surabaya, INDONESIA. 3Department of Pathology Anatomy, Faculty of Medicine/Dr. Soetomo General Academic Hospital, Universitas Airlangga, Surabaya, INDONESIA.&lt;/p&gt;
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