<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Cory Linda Futri Harahap</style></author><author><style face="normal" font="default" size="100%">Hakim Soleh Harahap</style></author><author><style face="normal" font="default" size="100%">Susi Yanti</style></author><author><style face="normal" font="default" size="100%">Elmi Sariani</style></author><author><style face="normal" font="default" size="100%">Anto J. Hadi</style></author><author><style face="normal" font="default" size="100%">Nefonavratilova Ritonga</style></author><author><style face="normal" font="default" size="100%">Haslinah Ahmad</style></author><author><style face="normal" font="default" size="100%">Hapiz Arlanda Sani</style></author><author><style face="normal" font="default" size="100%">Anwar Mallongi</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Testing the Effectiveness of Anti-Aging Cream Preparations with Snakefish Extract (Channa Striata)</style></title><secondary-title><style face="normal" font="default" size="100%">Pharmacognosy Journal</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Anti-Aging Cream</style></keyword><keyword><style  face="normal" font="default" size="100%">Formula</style></keyword><keyword><style  face="normal" font="default" size="100%">Snakehead Fish Extract</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2024</style></year><pub-dates><date><style  face="normal" font="default" size="100%">October 2024</style></date></pub-dates></dates><volume><style face="normal" font="default" size="100%">16</style></volume><pages><style face="normal" font="default" size="100%">1164-1169</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Background: &lt;/strong&gt;Skin aging is caused by dry, rough, scaly, less elastic skin with wrinkles and fold lines. Snakehead fish extract has high antioxidant activity so it can be used as an active ingredient in &lt;em&gt;antiaging cosmetics&lt;/em&gt;.&lt;strong&gt; Objective: &lt;/strong&gt;The aim of this research was to see the effectiveness of snakehead fish extract cream as an &lt;em&gt;anti-aging agent&lt;/em&gt;. &lt;strong&gt;Methods: &lt;/strong&gt;This research method includes formulating snakehead fish extract cream preparations with various concentrations including: 2.5% (F1), 5% (F2), 7.5% (F3), 10% (F4), evaluating the physical preparations in the form of: organoleptic test, homogeneity test, pH test, stability test, irritation test on volunteer skin, and&lt;em&gt; anti-aging effectiveness test&lt;/em&gt; on volunteer skin for 4 weeks with 3 parameter tests, namely water content, pores and wrinkles.&lt;strong&gt; Results:&lt;/strong&gt; The results of the study showed that there were changes that occurred in the volunteers as seen in the measurements of water content, pores and wrinkles on the volunteers' faces. A good increase in changes was found in the F4 formula (10%) in the wrinkle parameter test, namely 26.80%. The number of wrinkles in volunteers from some wrinkles to few wrinkles. The conclusion of this research shows that snakehead fish extract ( &lt;em&gt;Channa striata&lt;/em&gt; ) can be formulated in the form of a homogeneous cream dosage with a pH of 5.8 – 6.7, and is stable when stored for 12 weeks at room temperature and does not cause skin irritation. &lt;strong&gt;Conclusions: &lt;/strong&gt;There are differences in the results of each concentration of snakehead fish extract cream in influencing &lt;em&gt;anti-aging effectiveness&lt;/em&gt;. The best concentration of 10% snakehead fish extract showed better results compared to other creams in reducing the number of wrinkles on volunteers' facial skin.&lt;/p&gt;
</style></abstract><issue><style face="normal" font="default" size="100%">5</style></issue><work-type><style face="normal" font="default" size="100%">Research Article</style></work-type><section><style face="normal" font="default" size="100%">1164</style></section><auth-address><style face="normal" font="default" size="100%">&lt;p class=&quot;rtejustify&quot;&gt;&lt;strong&gt;Cory Linda Futri Harahap&lt;sup&gt;1*&lt;/sup&gt;, Hakim Soleh Harahap&lt;sup&gt;1&lt;/sup&gt;, Susi Yanti&lt;sup&gt;1&lt;/sup&gt;, Elmi Sariani&lt;sup&gt;1&lt;/sup&gt;, Anto J. Hadi&lt;sup&gt;2&lt;/sup&gt;, Nefonavratilova Ritonga&lt;sup&gt;2&lt;/sup&gt;, Haslinah Ahmad&lt;sup&gt;2&lt;/sup&gt;, Hapiz Arlanda Sani&lt;sup&gt;2&lt;/sup&gt;, Anwar Mallongi&lt;sup&gt;3,*&lt;/sup&gt;&lt;/strong&gt;&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;1&lt;/sup&gt;Department of Pharmacy, Faculty of Health, Aufa Royhan University, Padangsidimpuan, North Sumatra, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;2&lt;/sup&gt;Department of Public Health, Faculty of Health, Aufa Royhan University, Padangsidimpuan, North Sumatra, INDONESIA.&lt;/p&gt;

&lt;p class=&quot;rtejustify&quot;&gt;&lt;sup&gt;3&lt;/sup&gt;Department of Environmental Health, Faculty of Public Health, Hasanuddin University, Makassar, INDONESIA.&lt;/p&gt;
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